Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 117 for “"Inflammatory bowel disease (IBD)"”.
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The lived experiences of family planning for women with inflammatory bowel disease (IBD)
Inflammatory Bowel Disease (IBD) affects 1 in 400 people in the UK, with a prevalence of 397 per 100,000 among women, many of whom are of childbearing age. Women with IBD report heightened pregnancy-related anxieties, and their family planning decisions are complex and influenced by both medical …
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Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience
… 6-mercaptopurine (6-MP) in the treatment of Inflammatory Bowel Disease (IBD) are well established. However, concern regarding the long-term use of these agents in the induction of certain malignancies particularlty lymphoma and skin cancer has been reported in renal transplant and rheumatoid …
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Investigating a Mitochondrial Fission Inhibitor as a Therapeutic for Inflammatory Bowel Diseases
… for its possible role in the pathogenesis of inflammatory bowel disease (IBD). The current study utilized the P110 peptide drug, a selective inhibitor of mitochondrial fission, to investigate the relationship between mitochondrial dynamics and colitis. First, the functionality of the P110 …
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Coping Behaviors of African Americans with Inflammatory Bowel Disease: A focused Ethnography
… of African Americans are being diagnosed with inflammatory bowel disease (IBD) in the United States (Dahlhamer, Zammitti, Ward, Wheaton, & Croft, 2016). Little is known about the influence of culture on coping with the disease. Method: Twelve African American adults with IBD were interviewed …
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"Sometimes, I think I might say too much": Dark Secrets and the Performance of Inflammatory Bowel Disease
… explored. Comprised of a year of attending three Inflammatory Bowel Disease (IBD) support groups and semi-structured interviews with twelve support group members, this study sits at this intersection. The article first succinctly uncovers the contemporary boundaries of Cahill’s (2006) notion of …
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The Association Between Environmental Factors and the Risk of Paediatric Inflammatory Bowel Disease
Background: The incidence of inflammatory bowel disease (IBD) in children is increasing. Environmental factors related to industrialization, including increased levels of air pollution and reduced greenspace may be partially responsible. Methods: Health administrative data from Ontario were used to …
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Improving Provider Compliance With Adult Inflammatory Bowel Disease Patient Care Guidelines In The Ambulatory Setting Through The Use Of Electronic Health Records
… care necessary to treat adult patients with inflammatory bowel disease (IBD), using well-designed, evidence-based clinical decision tools or checklists within the workflow of the EHR system can improve provider compliance with IBD clinical practice guidelines. This initiative will result in …
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Macromolecular Complexes of Cystic Fibrosis Transmembrane Conductance Regulator Alter Fluid Transport in inflammatory Bowel Disorders
… synthase (iNOS) at the apical plasma membrane in inflammatory bowel disease (IBD). The complex formation requires the scaffolding protein Na+ /H+ exchanger regulatory factor 2 (NHERF2). We demonstrate that iNOS is overexpressed at or near the apical plasma membrane of gut epithelial cells in IBD …
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Colonoscopy cleanout education and outcome optimization
… of pediatric patients with known or suspected GI disease. Common indications for the procedure in pediatric patients include chronic diarrhea, hematochezia, or inflammatory bowel disease (IBD). In preparing a patient for colonoscopy, a regimen is typically prescribed, altering diet and fluid …
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DNA alkylation repair deficient mice are susceptible to chemically induced Inflammatory Bowel Disease
The two most common forms of inflammatory bowel disease (IBD) are ulcerative colitis (UC) and Crohn's Disease (CD), which affect more than 1 million Americans. Recently the incidence of IBD has been rising in Japan, Europe and North America.' Colorectal cancer is a very serious complication of IBD, …
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Using network inference to discover molecular pathways underlying cytokine synergism and age-related neurodegeneration
… shed light on molecular pathways underpinning diseases ranging from cancers to neurodegenerative disorders. However, effectively integrating information across these diverse data types is challenging. Network modeling approaches can help bridge this gap. In particular, the Prize- Collecting …
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Subject positions of British South Asian women with inflammatory bowel disease: a Foucauldian discourse analysis
The prevalence of inflammatory bowel disease (IBD) among British South Asians (BSA) is increasing. Evidence suggests that people of BSA background are more likely to develop IBD than white Europeans. Research on women with IBD is primarily focused on reproduction, which limits our understanding of …
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Inflammatory Bowel Disease, Health and Well-being: Definitions, Identity and Experience
… and well-being in the lives of individuals with Inflammatory Bowel Disease (IBD). Taking an auto/biographical approach and utilising in-depth qualitative online interviews, I draw on the experience and narratives of seventeen individuals with IBD, including myself. The three main themes addressed …
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MAdCAM-1 expression and function in human liver
… playing an important role in the development of inflammatory bowel disease (IBD). Recent studies have reported its expression in liver diseases such as primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) that complicate IBD, therefore understanding the factors that drive hepatic …
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Investigating the role of IL-4/IL-13 and their receptors in ulcerative colitis
Ulcerative colitis (UC) is a heterogeneous inflammatory bowel disease (IBD) associated with chronic inflammation of the gastrointestinal tract. Characterized by genetic and immunological abnormalities, UC has overly aggressive T-cell responses to commensal bacteria eventually leading to disease …
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Epithelial Cell Autophagy in Antibacterial Defense of the Small Intestine
… barrier, leading to pathologies such as inflammatory bowel disease (IBD), and bacteremia. As a result, epithelial cell innate immune responses play an essential role in preventing bacterial invasion of host tissues and maintaining a symbiotic host-bacterial relationship. Autophagy is …
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Prediction of nitric oxide concentrations during inflammation and carcinogenesis
… implicated in the development or progression of disease. Nitric oxide production in the colon has been linked to inflammatory bowel disease (IBD) and increased risk for colon cancer. However, measurements of NO concentration in the inflamed colon have not been available and it is not known what …
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Internalizing symptoms, medication adherence, and perceived social support in individuals with inflammatory bowel disease
… perceived social support for individuals with inflammatory bowel disease (IBD). Patients were recruited for this study from online forums consisting of Facebook support groups, Twitter followers, and email. This study investigated sociodemographic and disease-related predictors of disease …
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The Role of Short-Chain Fatty Acids on Intestinal Epithelial Cell Migration
Inflammatory Bowel Disease (IBD) is a chronic remitting and relapsing autoimmune disorder of the gastrointestinal tract that affects millions of people worldwide with incidence and prevalence on the rise. Increases in the rates of IBD have been partly attributed to shifts toward a western diet, …
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The Role of Dysfunctional Na+/H+ Exchange in the Development of Dysbiosis and Subsequent Colitis
… and alarming rise in the incidence of autoimmune disease in industrialized nations too rapid to be accounted for by genetics alone. Among those, Inflammatory Bowel Disease (IBD) has risen from a western disease affecting industrialized populations to an emerging global threat affecting diverse …
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