Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Inflammaging"”.
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Time-Restricted Eating and Prebiotic Supplementation in Young Adult Pediatric Cancer Survivors
… be a result of increased biological aging, or inflammaging, in this population. Anti-cancer treatment may initiate inflammaging promoting systemic inflammation and gut dysbiosis and cardiometabolic disease risk. Dietary behavior may further enhance inflammaging in the years following diagnosis …
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ULTRA-LOW LEVEL SOLUBLE P24 IS ASSOCIATED WITH INFLAMMATION IN PEOPLE WITH HIV ON LONG-TERM VIROLOGICALLY SUPPRESSIVE ANTIRETROVIRAL THERAPY
… measured at baseline: plasma biomarkers of inflammaging (Luminex/ELISA), CD38+CD8+ T-cells (flow cytometry), cell-associated total/unintegrated/integrated HIV DNA (qPCR). Mortality risk was estimated by VACS Index 2.0. In vitro experiments tested whether p24 modulates IP-10 secretion by …
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Innate Lymphoid Cell Characterization and Ilc2S In Neuroinflammation In Aging and Sex Differences
… inflammation throughout all systems, termed inflammaging. However, understanding healthy aging mechanisms can bypass this effect. Inflammaging also leads to poor outcomes during brain injury, making immune-targeting therapeutics tantamount to overall brain health and longevity. Moreover, sex …
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Identifying Endogenous Drivers of Chronic Disease Using Novel Computational Methods
terile inflammation, “inflammaging”, is a hallmark of aging and contributes to many age-associated diseases. Targeting the underlying mechanisms of inflammaging could have significant implications for the treatment of many chronic diseases. Cellular senescence (CS) and transposable elements (TEs) …
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Characterization of the Dunkin Hartley guinea pig as a non-transgenic and multimorbid model of brain aging
… however, have identified a dynamic whole-body "inflammaging" phenotype that exists with, and likely contributes to, AD/ADRD onset and progression. Currently, we do not have an accessible and tractable preclinical model that naturally mimics the age-related, systemic and progressive …
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Age-Dependent Variability in Immune Host Responses to SARS-CoV-2: Implications for Inclusive Clinical Trial Design
The COVID-19 pandemic, caused by SARS-CoV-2 has disproportionately affected older adults,who account for the majority of COVID-19-related hospitalizations and deaths. Although disease severity has declined, periodic surges continue to pose significant risks to aging populations, exacerbated by …