Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Infant mouse model"”.
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Characterization of a Low-Fidelity Live-Attenuated Vaccine for Venezuelan Equine Encephalitis Virus
… increased, albeit inconsistent attenuation in an infant mouse model, as well as increased immunogenicity and complete protection against lethal challenge of an adult murine model compared to the parent TC-83. The TC-83 3x mutant was selected for further study due its decreased replication …
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Investigations of enterotoxigenic E. Coli (ETEC) intestinal colonization in neonatal mice and human shedding of panchol, a new live attenuated oral cholera vaccine
… systems or little access to clean water. Infants and children are most vulnerable to these diseases, as severe infections can lead to stunting and death. The incidence of cholera and ETEC diarrhea have increased, due in part to changing weather patterns. At present, robust animal models …
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The Mechanism For Inhibition Of Vibrio Cholerae Virulence Gene Expression By Bile And Its Fatty Acid Components
… on both gene expression and DNA binding. In the infant mouse model, CLA did not inhibit colonization, but in the rabbit ileal loop model CT production was significantly decreased, suggesting that CLA may work to reduce cholera symptoms.</p> <p>In the last chapter, we looked at the possibility of …