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Showing 1 to 3 of 3 for “"Indole signalling"”.

  1. High level indole signalling in Escherichia coli

    Indole is a small signalling molecule, produced by many species of bacteria, including Escherichia coli. It is made by the enzyme tryptophanase, which converts tryptophan into indole, pyruvate and ammonia. Indole has diverse roles in E. coli, including regulation of biofilm formation, acid …

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  2. Tryptophanase Regulatory Mechanisms in Escherichia coli

    Indole is a heterocyclic signaling molecule, synthesized by a wide array of bacterial species, but most studied in *Escherichia coli*. Indole is formed by the degradation of L-tryptophan through the action of the enzyme tryptophanase (TnaA). The *tnaA* gene is part of the tryptophanase (*tna*) …

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  3. Quantifying passive drug transport across lipid membranes

    … Finally, we report on the discovery of a novel signalling mechanism in E. coli that relies on the transport of small drug-like molecules, and discuss the role it plays in stress response in the microbial community.

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