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Showing 1 to 3 of 3 for “"Indole arynes"”.
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Indole Arynes in organic synthesis : discovery and applications for the total synthesis of complex natural products
Arynes and heteroarynes are very important and useful reactive intermediates with many applications in organic synthesis, including natural products total synthesis. Although benzyne, the parent and most famous aryne, has itself been known for over 50 years, arynes derived from the ubiquitous …
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Part I. Computational, theoretical and synthetic studies of the indole arynes and their reactions. Part II. Computational, theoretical, and mechanistic studies of n-vinyltrialkylammonium, n-vinylpyridinium, and n-vinyldiazonium tetrafluoroborate salts.
… discovery and first report by Buszek in 2007, Indole arynes have been established as an invaluable synthetic tool in the total synthesis of many complex natural products of biological and medicinal significance. Of particular interest are polyhaloindoles, which we have exploited for their …
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Recent Advances in Indole Aryne Cycloaddition Chemistry. Part I: Total Synthesis of (±)-cis-Trikentrin B. Part II: Investigation into the Regioselectivity of 6,7-Indole Aryne Cycloadditions. Part III: Synthesis and Reactions of Novel Tribromoindoles
… in the Buszek laboratories in 2007, the indole arynes and their cycloaddition chemistry has demonstrated its significance in achieving the total synthesis of biologically active indole alkaloid natural products such as the trikentrins and herbindoles in a facile manner. The application of …