Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"In vivo exposure"”.
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Assertion training and in vivo exposure as treatment for agoraphobia
… 50%-60% of all phobic clients seen by practicing mental health professionals. The syndrome includes fears of leaving home, being in closed spaces, shopping, and traveling especially when alone. There is much fear generalization throughout the course of the disorder, and numerous other symptoms …
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An electrophoretic study of fetal mouse brain proteins after in vivo exposure to phenytoin and disulfiram
… electrophoretic studies on fetal brain tissue (for instance, Yoshida and Takahashi, 1980), the emphasis in most of this work has been on developmental changes in protein expression, and not on the effects that drugs have on fetal brain protein complement. Klose and co-workers (1977) …
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The enduring impact of one-session exposure treatment on selective processing bias and explicit memory avoidance in snake- and spider-fearful participants
<p>The prevalence of anxiety disorders in the general population makes clarification of variables that contribute to the onset or maintenance of these disorders essential. Two such contributory variables are anxiety-induced selective processing bias and theorized subsequent explicit memory …
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Virtual reality exposure therapy as a psychological intervention for public speaking anxiety
… of the efficacy of virtual reality and in-vivo exposure therapy as psychological interventions for public speaking anxiety." Note this is a meta-analysis (form of literature review).<br/><br/>Public speaking anxiety (PSA) is a highly prevalent condition which can be associated with …
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Cholinergic signals promote the quiescence of normal or leukaemic stem cells through the activation of the α7-nicotinic receptor in bone marrow mesenchymal stromal cells
… and activates haematopoietic stem cells (HSCs) using noradrenergic signals. However, the pathways that maintain HSC quiescence and maintenance during proliferative stress are not well understood. This study has investigated the role of cholinergic signals during healthy and malignant …
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Nitric oxide : cellular effects in vitro and in vivo
The overall aim of this project was to investigate various cellular responses and toxic effects of nitric oxide, NO' and in vitro and in vivo. Nitric oxide gives rise to a complex spectrum of reactive species in oxygenated solution. The complexity of nitric oxide's chemistry is recapitulated in its …
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The analysis of radiation-induced micronuclei in peripheral blood lymphocytes for purpose of biological dosimetry
In the investigation of radiation accidents, it is of great importance to estimate the dose absorbed by exposed persons in order to plan their therapy. Although occasionally in these situations physical dose measurements are possible, most often biological methods are required for dose estimation. …
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An Internet-Based Self-Change Program for Trauma Sequelae
The purpose of this study was to examine whether a newly developed Internet-based, eight-week self-change program, Self-Help Intervention Program for the Consequences of Trauma (SHICT), was effective to treat trauma consequences. The SHICT consisted of education, anxiety management skills, …
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Understanding Craving for Cigarettes: A Multidimensional Assessment Approach
<p>Cigarette smoking is a serious health hazard affecting a sizeable proportion of the adult population. The addictive nature of cigarettes has been blamed for the difficulty smokers experience in achieving and maintaining abstinence. Cigarette cravings are frequently cited as a factor contributing …
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“Vicarious Exposure”: Experimental Studies Towards Developing Novel Therapies for Obsessive-Compulsive Disorder
… disorder (OCD) patients fail to respond to any kind of treatment. Developing novel therapies for OCD—the aim of this thesis—therefore represents an urgent unmet need. Study 1 examined vicarious contamination sensations and relief in OCD. Study 2 explored the therapeutic utility of the “rubber …
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Early Effects of Organophosphate Compounds on In Vitro Intracellular Signaling and Levels of Active Neurotrophin Receptors, and on In Vivo Neurotrophin Concentrations
Organophosphorus (OP) compounds are found in household pest control products, plastics, and petroleum. Due to the neurotoxic nature of OP compounds, exposure can cause both acute and delayed symptoms, including organophosphate-induced delayed neuropathy (OPIDN). This syndrome is characterized by …
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Mechanisms of Innate Immune Dysfunction During Mycobacterium tuberculosis and HIV Co-infection
… the etiologic agent of Tuberculosis (TB), remains a significant public health threat causing over 1.4 million deaths annually. People living with HIV are among the most susceptible to contracting or reactivating Mtb infection due to a deterioration of essential immunity during co-infection. …
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The influence of mine waste contamination on invertebrates and fish in the Methow River Valley, Okanogan County, Washington (U.S.A.)
A study of mine-waste contamination effects on Methow River habitat on the eastern slopes of the north Cascade Mountains in Washington state, U.S.A., revealed trace element impacts on invertebrates and fish. Ore deposits in the area were mined for gold, silver, copper and zinc until the early …
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Durability of glass and ceramic fibres within the lung.
The durability in the lung of inorganic fibrous materials, such as asbestos and man-made mineral fibres, appears to be a major determinant of their pathogenic potential. However, studies have been inadequate in explaining differences in the physiological durability of such inorganic fibres.This …
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Effects of estrogen on the B cell functions of normal mice
… that reproductive hormones such as estrogen influence not only classical targets (eg. reproductive tissues), but may also act on non-classical target sites such as the immune system. A better understanding of the effects of estrogen on the immune system is of paramount importance since: (i) …
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Studies on the Interaction between Porcine Plasmacytoid Dendritic Cells and Porcine Reproductive and Respiratory Syndrome Virus
For over 20 years, porcine reproductive and respiratory syndrome (PRRS) has been the most troubling disease afflicting the pork industry. The main reason for this dissertation is that the pathogen responsible for this disease, PRRS virus (PRRSV), has developed the ability to subvert the immune …
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Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
… represent the two most prevalent parasitic infections with grievous repercussions on the socio-economic development of affected countries, mainly in sub-Saharan Africa and South-East Asia. Despite their ravaging effects, the treatments of these two diseases have been committed to a limited …