Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"In silico optimisation"”.
-
Construction and Biological Characterisation of Custom Engineered Protein Degradation Tools.
Event-driven pharmacology is a new paradigm in disease treatment for a wide range of diseases, including cancer, that have failed by traditional occupancy-driven pharmacology. One target that has been resistant to conventional inhibition approaches is Aurora A (AurA). Degradation rather than …
-
Design of flow processes for C–H activation-type reactions
The last 15 years have seen tremendous advances in using different metal catalysts to functionalize traditionally unreactive C–H bonds. Given the high potential of these seemingly ideal strategic bond forming reactions, the uptake of C–H activation in fine chemical manufacture is slow. Part of the …
-
Predictive simulation and design of III-V heterostructures for light emission and detection
… for a variety of applications, particularly in photonic devices such as light-emitting diodes (LEDs) and lasers, in addition to photodetectors and optical amplifiers. Predictive simulations are key to support the development of these technologies. In this Thesis we employ both …