Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Importin alpha"”.
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Feedback Regulation of Wnt Signaling by Naked Cuticle (Nkd) During Drosophila Embryogenesis
… of Nkd's role in the nucleus, Nkd binds to Importin-alpha 3, an adaptor for the canonical nuclear import apparatus. I identified that Nkd associates with Importin-alpha 3 via a motif ("D6") that is conserved between D. melanogaster and D. pseudoobscura. NkdΔD6, lacking the Importin-alpha …
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Charakterisierung der viralen Genprodukte p10 und P des Borna Disease Virus
… zeigten, dass p10 über den klassischen Importin alpha/beta abhängigen Kernimportweg in den Nukleus transportiert wird. Dies war unerwartet, da p10 kein vorhersagbares klassisches Kernlokalisierungssignal (NLS) besitzt und weist darauf hin, dass der zelluläre Importapparat offensichtlich …
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LNX1 and LNX2 in the central nervous system: linking behavioural, cellular and molecular perspectives
… further revealed that LNX1 NLS interacts with importin alpha family members, supporting its role in regulating LNX1 nuclear translocation. Altogether, these findings revealed distinct, non-overlapping neuronal functions of LNX1p70/p62 and LNX2, linking them to behavioural phenotypes relevant to …
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Cell cycle-dependent regulation of the human RNA cap methyltransferase (RNMT)
… regulates the interaction of RNMT with KPNA2 (Importin-a), which was found to inhibit RNMT activity in vitro. RNMT T77 phosphorylation is required for normal cell proliferation suggesting an important biological function. Initial experiments indicated that RNMT T77 phosphorylation functions to …