Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Immunostimulant"”.
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Augmentation of Natural Killer Cell Activity by CORYNEBACTERIUM PARVUM: Involvement of Lipoxygenase Pathway
… for determining the effectiveness of this immunostimulant. <em>In vitro</em> manipulations of nordihydroguaiaretic acid, indomethacin, and prostaglandin E2 on CP-stimulated NK cells suggest that the lipoxygenase pathway is involved in NK lysis.</p>
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The Effect of Leucogenenol and Chemotherapy on Leukemia L1210
… the effect of leucogenenol, an untried immunostimulant, in conjunction with known effective chemotherapy on mouse leukemia L1210. Procedure. L1210 infected animals in various treatment groups were monitored for changes in several parameters of the disease. Among these parameters were …
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Anti-inflammatory Role of IL-15Rα Up-regulated by Poly I:C in Herpes Simplex Virus-induced Behcet's Disease-like Mouse Model
… Polyinosinic:polycytidylic acid (Poly I:C) is an immunostimulant which boosts the generation of memory T cells though induction of IL-15 and IL-15Rα. We found that the frequencies of IL-15Rα were significantly lower in HSV-induced BD mouse model than control mice. Therefore, this study was …
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The Effect Of Leucogenenol and Chemotherapy on B and T Lymphocyte Populations in Mice Infected With Friend Virus Leukemia
… were designed to determine the effects of the immunostimulant leucogenenol and the combination chemotherapy of arabinosyl cytosine and vinblastine on the Band T lymphocyte populations of mice infected with Friend virus leukemia. Procedure. Isolated lymphocyte populations were quantitated using …
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Drug design strategies for modulating immune activity for the treatment of autoimmune diseases and cancer
… to help deliver CpG, a negatively-charged immunostimulant. We previously demonstrated that this polyplex formulation can help increase tumor retention and limit systemic toxicity. Here, we investigated whether this polyplex formulation can be used in combination with anti-PD-1 therapy to …
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CHARACTERIZATION AND PATHOLOGICAL STUDY OF A. HYDROPHILA IN WALKING CATFISH (CLARIAS GARIEPINUS)
… studied in immunized fish or fish injected with immunostimulant, complete Freund's adjuvant (CFA). The results of this study indicated that the virulence of each isolated Aeromonas hydrophila was different from one another, even though they had the same biochemical characteristics. No specific …
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Study of apoptotic deletion mediated by Bifidobacterium longum with construction of recombinant strains for Serpin encoding gene and phenotypes comparison in a pig cell model
… apoptosis induction. Bifidobacterium longum has immunostimulant activity that in vitro can lead to apoptotic response of Caco-2 cell line. It secretes a hypothetical eukaryotic type serpin protein, which could be involved in this kind of deletion of damaged cells. We had previously characterised …
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Layer-by-Layer Nanoparticles for Cytokine Delivery
… is used for targeted delivery of a potent immunostimulant – interleukin-12 (IL-12) to disseminated tumors in metastatic OC. Aspects on the manufacturing of other lipid-based nanocarriers such as discoidal assemblies and immune stimulating complexes (ISCOMs) are also explored. We show that …
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Analysis of the Immunomodulatory Properties of Mycobacterium Cell Wall Fraction on the Cytokine Production of Peripheral Blood Mononuclear Cells of Healthy Dogs
Mycobacterium cell wall fraction (MCWF) is a Toll-like receptor agonist that is derived from non-pathogenic Mycobacterium phlei. The objective of this research was to evaluate host responses induced by MCWF in canine peripheral blood mononuclear cells (PBMCs), using enzyme-linked immunosorbent …