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Showing 1 to 1 of 1 for “"Immunoquantification"”.
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Determination of Absolute Protein Content of Hepatic CYP4F Enzymes in Human Liver Microsomes Using LC/MS/MS Methodology and Comparison with Immunoquantification and Enzyme Activity
… determined by LC/MS/MS were well correlated with immunoquantification results (r2 ≥ 0.60) for both CYP4F and CYP3A. The CYP4F enzymes displayed significantly less (~2- to 4-fold) variability than did the CYP3A enzymes (~7- to 20-fold). The CYP4F protein contents did not correlate with primary …