Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"Immunopathogenesis"”.
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The Immunopathogenesis of HLA B27-associated Spondylarthritis and Acute Anterior Uveitis
HLA-B27 is a Class I Major Histocompatability Molecule that is highly prevalent in patients with Acute Anterior Uveitis (AAU) and Seronegative Arthritis (SNA). Despite over 40 years of research, the pathogenic mechanism of HLA-B27-related disease remains elusive. The bacterium Chlamydia trachomatis …
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Diagnosis, treatment and immunopathogenesis of the HIV-associated tuberculosis immune reconstitution inflammatory syndrome
The paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is a frequent complication of antiretroviral therapy (ART) among patients who start ART while on treatment for tuberculosis (TB). The condition manifests with new, worsening or recurrent inflammatory …
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Equine Protozoal Myeloencephalitis: investigating immunopathogenesis and treatment efficacy in mouse models and clinically affected horses
Equine protozoal myeloencephalitis (EPM), predominantly caused by the protozoa Saracocystis neurona, is a common neurologic disease in horses from North America. Equine exposure to the parasite occurs frequently as the protozoa is excreted in opossum (Didelphis virginiana) feces and contaminates …
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On the immunopathogenesis of systemic lupus erythematosus - Immune complexes, type I interferon system, complement system and platelets
… immune complexes (ICs) which are central in the immunopathogenesis of SLE. Through activation of the complement system, ICs mediate tissue destruction, and through interaction with immune cells ICs induce large amounts of pro-inflammatory cytokines, including IFN-alpha. Furthermore, ICs might …
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Elucidating the Role of Antigen-presenting Cells in the Immunopathogenesis of the Porcine Reproductive and Respiratory Syndrome Virus
… to the general knowledge surrounding the immunopathogenesis of PRRSV. Future work investigating the mechanisms by which PRRSV hinders the progression to adaptive immunity could prove to be fundamental in the development of a novel vaccine.
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Identification of macrophage phenotypes and evaluation of their role in the immunopathogenesis in animal model of Behçet’s disease
Although several immunological abnormalities have been demonstrated in Behçet’s disease (BD), the exact mechanism of the inflammatory changes occurring during the development of this disease remains unclear. Macrophage phenotypes are markedly heterogeneous and include classically activated (M1) and …
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Immunological characterization of the HIV-tuberculosis associated immune reconstitution inflammatory syndrome
… diseases. This work aimed to characterise the immunopathogenesis of paradoxical HIV-Tuberculosis associated immune reconstitution inflammatory syndrome.
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Mechanistic Insights on The Immunomodulatory Functions of Diverse Environmental Factors on Systemic Autoimmunity
… influence of environmental factors on their immunopathogenesis, where environmental factors could either hinder or contribute to autoimmune development. We focused our research on deciphering the complex effects of environmental factors on the immunopathogenesis of systemic immune …
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Neuronal Toxicity of Humoral Factors From Patients With Diabetic Neuropathy and Mechanism of Neuronal Death on Cultured Adrenergic Neurons: Studies of Autoimmune Pathogenesis in Diabetic Neuropathy
… neuropathy. However, the significance of immunopathogenesis of diabetic neuropathy is as yet unclear.</p> <p>Using the N1E-115 mouse neuroblastoma cell line (NB) as a model of the adrenergic autonomic neuron, we found that sera of IDDM patients with neuropathy inhibit growth and …
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The Effect of Primary Hepatocyte Expressing HBx on the Activation and Apoptosis of Antigen-specific CD8+ T Cell
… B virus, plays an important role in the immunopathogenesis of HBV infection. Since HBx is able to upregulate cellular expression level, it is thought that HBx may modulate CD8^(+) T cell immune response. To test this hypothesis, proliferation, cytokine production and apoptosis of CD8^(+) …
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The Balance of Interferon-γ and Interleukin-10 during Influenza A Virus Infection Complicated by Methicillin-Resistant Staphylococcus aureus Superinfection
… IFN-γ and IL-10 that shifts the balance between immunopathogenesis and bacterial outgrowth.
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Abscisic acid ameliorates glucose tolerance and obesity-induced inflammation
… in general, expand our knowledge concerning the immunopathogenesis of obesity-induced insulin resistance.
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Screening and Functional Analysis of New Anti-Complement Autoantibodies in the Course of Systemic Lupus Erythematosus // Скрининг и функционален анализ на нови анти-комплементни автоантитела в хода на системен лупус еритематодес
… immune defence, plays a significant role in the immunopathogenesis of SLE and LN. This role is seen as twofold: on the one hand, activation of the complement cascade involving the mechanisms of innate and acquired immunity leads to the development of inflammation, the immune response to …
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CD4+ T cells in the pathogenesis of visceral leishmaniasis
… understanding of the mechanisms involved in immunopathogenesis of chronic visceral leishmaniasis.
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The innate immune response to HSV-1: glycoprotein mediated activation of dendritic cells
… important implications not only in understanding immunopathogenesis, but also in the study of HSV-1 as an immunotherapeutic vector, and in the design of an efficient HSV-1 vaccine. Monocyte-derived DCs (MDDC) were found to recognise and respond to the complex of four essential viral glycoproteins, …
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The Level of Antiacetylcholine Receptor Antibodies in the Patients with Myasthenia Gravis
… test (RNS). Some cytokines were related to immunopathogenesis of MG, but there was no report which cytokines were affected by immunotherapy. The authors studied which factors correlated with the level of antiacetylcholine antibodies and which cytokines were affected by immunotherapy. Thirty …
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Immune function alterations in Asian elephants (Elephas maximus) infected with Mycobacterium species
… granuloma walls. The information on tuberculosis immunopathogenesis gained by this study represents a foundation for investigation of the immune response to this disease in elephants. The results indicated that distinguishing features do exist in systemic immune responses between positive and …
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