Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Immunological Methods"”.
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Purification, immunogenicity and protective potency of the F1 antigen from <i>Yersinia pestis</i>
… characterised using biochemical, structural and immunological methods to confirm the integrity of the purified antigen. Immunological methods using anti-F1 monoclonal and polyclonal antibody identified the purified antigen as F1. Structural studies on the glycosylation of the protein showed that …
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Inhibition of horseradish peroxidase activity by specific antibody
… horseradish peroxidase isoenzymes were used in immunological procedures (precipitation, anticatalytic assays) to assess the homology of horseradish, radish and turnip peroxidases. Acidic horseradish peroxidases with similar physicochemical properties are distinguishable by immunological methods. …
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QSAR study of immunotoxicity in antibiotics.
… major drawback to the ~-lactams is the degree of immunologically adverse reactions they induce. It was the aim of this study to develop both mechanistic and immunological methods to enable the prediction of a B-lactam's potential to induce an allergic response and to determine if a relationship …
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Regulation of the catalytic and allosteric properties of photoreceptor phosphodiesterase (PDE6) by the glutamic acid-rich protein-2 (GARP2)
… in rod photoreceptors. We first improved immunological methods to better characterize GARP2. We then developed approaches to purify PDE6 free of GARP2; we also generated recombinant GARP2 to permit study of its biochemical and biophysical properties, and discovered that recombinant GARP2 …
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Identification of Lung Carcinoma Biomarkers Associated with Tumour Development and Drug Resistance
… of significant results was performed using immunological methods and biochemical assays. These studies have yielded valuable information that has unravelled several key molecular events of lung cancer tumorigenesis, including proteomic signature of lung cancer in BALF, tissue and blood. BALF …
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Molecular analysis of wet rot organisms: application to conservation of maritime artifacts
… relatively unsophisticated but effective methods of detecting decay in maritime artifacts are utilised but only detect decay once substantial structural damage has occurred. The potential of immunological methods for the <i>in situ </i> detection of antigens of <i>C. puteana, </i>prior to …
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In Situ Diagnostics for Multiple Allergens in Food
As the offshore wind industry moves into areas of deeper water, traditional foundation structures such as monopiles will become less economically feasible. This has generated a push for the development of floating turbines, which are held in place by mooring lines with anchor foundations in the …
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Composition and Dynamics of the Plasma Membrane of Entamoeba Histolytica
… in the development of pharmacological and immunological methods of control of the parasite. The subject of this thesis, the parasitic amoeba Entamoeba hystolytica, is an ideal subject for such research. While the pathogenic form may be grown in vitro, it is in nature an obligate parasite. …
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The Isolation and Characterization of Soluble Brain Proteins
… investigation of their tissue specificity, using immunological methods. For this purpose antisera to rat brain extracts were prepared. About twelve antigenic components could be demonstrated by immunoelectrophoresis; most were present in extracts of other tissues as well. The various antigens, …
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A mechanistic assessment of novel anticancer drugs targeting the metastatic cascade and tumour vascularisation.
… tumour cells lines and various biochemical and immunological methods to clarify their molecular and cellular mechanism of action. Both antimetastatic and antivascular activity of the best derivatives were assessed in vitro by using endothelial or tumour cell-based assays or in vivo by analyses …