Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Immunologic response"”.
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Patterns and associations with immunologic response in patients accessing ART in Khayalitsha
… the reported favorable outcomes in terms of immunologic responses, the actual variations in patterns of and associations with immunologic response over time among adult patients accessing the community based antiretroviral treatment programme in Khayelitsha are largely unknown. [The aim of …
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Quantifying the Effect of Vitamin D Deficiency and Alcohol Exposure on Immune Response to Mycobacterium Infection
… our understanding of the mechanisms guiding immunologic response. Previous studies on the role of vitamin D3 and its modulation of host response have shown increased anti-inflammatory cytokines and effector substrates during innate immune response; however, many of these studies investigated …
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Overcoming therapeutic resistance in glioblastoma using novel electroporation-based therapies
… stimulate local and systemic anti-tumor immune responses without significant morbidity. The following work explores the use of H-FIRE to overcome GBM-induced therapeutic resistance and improve treatment success. Chapter 1 opens with an overview of GBM and known barriers to treatment success. …
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Biobehavioral responses to immune skew and free fatty acids
… and the endogenous cytokines elaborated in the immunologic response are key effectors (Dantzer et al., 2008). Just as an organism’s response to a pathogen is defined by the host immune system status, so too is the basal cytokine environment altered by the endogenous immune skew (Gordon and …
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Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells
… devastating disease that is caused by the host’s response to an overwhelming infectious process. As sepsis progresses, organs distant from the site of infection become affected and sepsis-induced multiple organ failure ensues. An impaired immunologic response, including dysfunctional peripheral …
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Differential Expression of T Cell Immunoglobulin- and Mucin-Domain-Containing Molecule-3 (TIM-3) According to Activity of Behçet's Disease
… cell surface molecule that regulates TH1 responses and promotes tolerance in mice. Increased TH1 immune response has been known as one possible pathogenesis of a chronic inflammatory multisystemic disorder, Behçet’s disease (BD). However, TIM-3 expression and function in BD has not been …
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Mechanical High-Intensity Focused Ultrasound (Histotripsy) in Dogs with Spontaneously Occurring Soft Tissue Sarcomas
… and the potential to generate systemic immune response against tumor cells. Soft tissue sarcomas (STS) are a common form of cancer in dogs with biological behavior similar to STS in humans. Long-term tumor control requires complete removal with extensive surgical resection, which in many cases …
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Universal antiretroviral therapy (ART) for infants and young children living with HIV: assessing the effect of guideline changes on ART initiation characteristics and treatment outcomes in resource-limited settings
… initiation of ART, regardless of clinical or immunologic status initially for infants, and subsequently for progressively older, and ultimately all children. Given the scale-up of early infant diagnosis (EID) and early initiation of ART for infants and young children who are especially …
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Bi-directional tumour-host interaction in a murine model
Tumours evoke immunologic responses yet they continue to grow and develop. The majority of people who develop tumours are immunocompetant, evoke immune responses and yet metastases occur in lymphnodes, potentially the most hostile immune environment. This is the paradox that we are attempting to …