Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Immunologi"”.
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Development and application of monoclonal antibodies in studies of the human leukotriene B4 receptor, BLT1
Infection and inflammation are characterized by the release of chemotactic substances that activate cells of the immune system. One of these important mediators is LTB4, an arachidonic acid derivate that attracts e.g. monocytes and granulocytes to inflammatory sites and induces phagocytosis and …
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Studies on the genetic basis of Pk, P and P1 blood group antigen expression
The clinically important carbohydrate P/GLOB blood group systems and collection give rise to both common (P1, P2) and rare (p, P1k, P2k) blood group phenotypes. The associated antibodies are implicated in severe transfusion reactions and recurrent spontaneous abortions. The aim of this study was to …
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Natural killer T cell subsets and regulation of autoimmune diabetes
… suggested to play a role in several different immunological situations, such as clearance of pathogens, tumor rejection and regulation of autoimmune reactions. The broad spectrum of their activities suggested that functionally different subsets of NKT cells might exist. We have been able to …
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EFFECTOR T CELL HOMING TO THE SMALL INTESTINAL MUCOSA
The intestinal mucosa, including the intestinal epithelium and underlying lamina propria (LP), contains a large number of effector/memory T cells that are thought to play a central role in the generation and maintenance of mucosal immune responses and in maintaining mucosal integrity. The work in …
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Genetic Characterisation of Human ABO Blood Group Variants with a Focus on Subgroups and Hybrid Alleles
ABO is the most important blood group system in transfusion medicine and transplantation immunology. The ABO blood groups differ by the presence or absence of antigens on RBCs and antibodies in plasma. Accurate determination of ABO status is critical. Genomic typing can increase the precision of …
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T-cells in COPD to help or harm? A study of T-cells in COPD patients and related aspects of T-cell function in vitro
Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the …
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Immuno-modulatory functions of CD1d-restricted natural killer T cells
… NKT cells are involved in a cohort of diverse immunological situations, including immune responses to tumors, pathogens, and autoimmunity, where both protective and detrimental roles have been described. In order to learn more about what genes are important for the characteristic features of …
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Diagnostic and prognostic aspects of anti-neutrophil cytoplasmic antibodies in systemic vasculitis
Primary systemic vasculitis is associated with a high mortality if left untreated and it is essential to make the diagnosis before permanent organ damage has occurred. In this thesis the diagnostic and prognostic significance of anti-neutrophil cytoplasmic antibodies (ANCA) in systemic vasculitis …
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Epidemiology of diabetes in a well defined population in Sweden: the Skaraborg Diabetes Registry
Time trends in prevalence, incidence and mortality was followed in 15000 diabetic patients in 1991?2005. Clinical findings, C-peptide protocols, and islet antibodies were compared in their ability to distinguish type 1 from type 2 diabetes, and factors associated with the prognosis of diabetes were …