Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"Immunohistological"”.
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The Immunohistological Features of Acquired Bilateral Nevus of Ota-like Macules: Comparison with Melasma and Nevus of Ota
… facial skin. The routine histological and immunohistological findings of NKI/beteb, stem cell factor (SCF), c-kit, factor VIIIa-related antigen and vascular endothelial growth factor (VEGF) were examined and quantified by image analysis. RESULTS: In ABNOM, the amount of lesional dermal …
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The Parotid Salivary Glands. I. Potential Role of a Parotid Factor Modulating Pancreatic β-Cell Function. II. An Immunohistological Study to Identify Parotid Hormone Secreting Cell(s)
… levels than sham-operated controls.</p> <p>Immunohistological techniques were employed in an attempt to identify the particular cell(s) in the parotid gland responsible for production of parotid hormone. Even though our data were not conclusive, they suggest that cells associated with …
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Investigating Murine Uterine Tissue Dynamics: Biomechanical and Histological Perspectives on Postpartum Involution and Scar-Induced Remodeling
… such as Optical Coherence Tomography (OCT) and immunohistological staining will provide insights into tissue structure. Ultimately, this project aims to unveil the connection between uterine involution, scar healing, and uterine tensile strength.</p>
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Detection of periodontal bacteria in atherosclerotic plaque
… plaque tissue from the carotid artery. Immunohistological examination of the atherosclerotic plaque tissue revealed widespread localisation of the bacterial cell wall constituent peptidoglycan (PGN). Targeted PCR amplification of the 16S rRNA gene permitted identification of a diverse …
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Ex-vivo Untersuchungen zur Arzneimittelwirkung topischer Tacrolimus (FK-506) Anwendung auf epidermale dendritische Zellen in läsionaler Haut bei Patienten mit atopischem Ekzem
… DC populations in lesional AD. METHODS: Immunohistological analysis, epidermal DC phenotyping, and functional studies were performed on skin biopsy specimens from treated and untreated lesional skin of 10 patients with AD participating in a clinical trial with tacrolimus. RESULTS: …
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A cell level automated approach for quantifying antibody staining in immunohistochemistry images. A structural approach for quantifying antibody staining in colonic cancer spheroid images by integrating image processing and machine learning towards the implementation of computer aided scoring of cancer markers.
Immunohistological (IHC) stained images occupy a fundamental role in the pathologist¿s diagnosis and monitoring of cancer development. The manual process of monitoring such images is a subjective, time consuming process that typically relies on the visual ability and experience level of the …
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Pathological role of double-stranded DNA antibodies in multiple sclerosis.
… inflammatory phase of disease was profiled using immunohistological and ELISA methods and was related to clinical sign severity. The parameters of interest were central nervous system deposits of IgM, IgG, B cells and C3 and anti-DNA antibodies in sera, cerebrospinal fluid and in situ. In situ …
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Traumatic Brain Injury Accelerates Alzheimer’s Disease Pathology in the TgF344-AD Rat Model
… were sacrificed, and the brains were removed for immunohistological analyses of Aβ, p-Tau, and neuroinflammation. Results: TBI TgF344-AD rats performed significantly worse in the beam balance, beam walk, and neuroscore tests on days 1-3 post-injury when compared to the Tg sham and naïve groups (2- …
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The Distribution of Bone Sialoprotein in Bone Mineralization
… of mineralized bone and growth patterns. Immunohistological sections were made of each bone type to try to identify the organization of the BSP in each. BSP was found to be a component of the organic matrix. Moreover, BSP was more concentrated in areas where there was active mineralization.
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An Insight into Alpha-Synulcien's Biological Function and Its Pathogenesis in Neurodegenerative Disease
… logy characteristic of Parkinson's disease. Immunohistological studies revealed the presence of alpha -synuclein inclusions and a loss of motor neurons. Biochemical analysis identified a 4-5 fold increase in ubiquitin with altered expression of proteasomal subunits, characteristic of …
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Effects of Liposome-Encapsulated TNF-Alpha and Radiation against Colon Cancer
… were performed on the blood and the spleen, and immunohistological analyses were completed on the tumor excised from the mice.</p> <p>Collectively, the data of this research demonstrated for the first time that the addition of SL-TNF-α to radiation results in more than additive tumor growth …
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Functional and Molecular Aspects of Xenobiotic Transport in Choroid Plexus
… associated protein 1, were assessed by RT-PCR, immunohistological staining and in Western blots of isolated membrane fractions. Integrity of fully differentiated monolayers was ensured by TEER measurements as well as permeability analyses using marker compounds. Further, functional analyses of …
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The Genetic Basis Of Neurodegenerative Diseases: The Role Of Sel1L In Tau Pathology And Neuropathology
… broad deficits in spatial memory and learning. Immunohistological analysis revealed a perturbed dendritic network in the cerebral cortex. Cultured SEL1L-deficient primary neurons of the cerebral cortex displayed impaired dendritic growth. Furthermore, Fluoro-Jade C staining revealed an increased …
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Investigating neural responses in models of neurocysticercosis
… by Taenia crassiceps homogenate injection. Immunohistological analysis of the tissue below the injection site revealed no difference in astrocytes nor the number of microglia. However, microglial processes were observed to be retracted in the Taenia crassiceps group reflecting a moderate …
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Unique Features and Neuronal Properties in a Multisensory Cortex
… present experiments utilized a combination of immunohistological, neuroanatomical and multiple single-channel electrophysiological recording techniques. These experiments produced four main results. First, convergence of extrinsic inputs from unisensory cortical areas predominantly in layers …
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Vulnerability of ex vivo α-motor nerve terminals to hypoxia-reperfusion injury.
… system combined with quantitative assessment of immunohistological preparations as well as some ultrastructural observations, I present evidence to show that α-motor nerve terminals are rapidly and selectively vulnerable to hypoxia-reperfusion injury with no apparent perturbations to postsynaptic …
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HIV neutralization through use of antibodies and pharmacokinetics of topical applications
… the epithelium, ranging from 0.005% to 0.09%. Immunohistological data showed that antibodies applied apically to tissue models concentrated only in the superficial layers of the stratum corneum and did not penetrate the epithelium. Our data indicate that anti-HIV MAb-Ns are effective in …
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Model for tooth development in vitro
… visible after 4 hours. From protein analyses by immunohistological staining, after 4 days of condensation, the ECM components Tenascin, Fibronectin, Collagen type I and type IV were present in the DPC condensates. Long-term cultures of DPC condensates (4 weeks) showed odontogenic differentiation …
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Characterization of Fc receptor family proteins in vaginal and endocervical epithelia
… were detected by microarray in both models. Immunohistological staining revealed pIgR protein in the endocervical mucosal epithelium, confirming current literature describing its expression in the FRT and role in local production of cervicovaginal secretions. FcRn protein expression was …
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Einfluss der endo-lysosomalen Qb-SNAREs Vti1a und Vti1b auf die subzelluläre Sortierung sowie auf signalgebende Prozesse im zentralen Nervensystem der Maus
… CA1 subfield in situ, as demonstrated by immunohistological examination of Vti1a/Vti1b-double deficient embryonic brain tissue sections. However, an analysis of the ER showed no striking alterations in Vti1a-/- Vti1b-/-neurons. Since earlier investigations have already demonstrated an …
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