Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Immunohistochemistry staining"”.
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Magnetic Resonance imaging of tumour biomarkers in ovarian cancer
… semi-quantitative measurements of histology and immunohistochemistry staining of tissue samples. It was found that DKI may predict responders to cytotoxic drugs and that sodium MRI and MT measure cellularity. Effective techniques to perform hyperpolarized carbon-13 MRI and MRF were also shown in …
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Targeted Inhibition of Sp1 Transcription Factor and Anti-Angiogenesis of Human Pancreatic Cancer
… pancreatic cancer patients specimens through immunohistochemistry staining. The impact of Sp1 expression alternation on angiogenesis and tumor progression in nude mice were determined by knockdown Sp1 with small-interfering RNA (siRNA). Sp1 protein expression was correlated with the MVD (P < …
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Design, Synthesis, and Evaluation of a Novel Cytotoxic Peptide-Doxorubicin Conjugate Targeting Triple-Negative Breast Cancer
… cell lines and a normal breast cell line using immunohistochemistry staining suggested that cell-surface expression of K1 in normal breast MCF-12A cell line is much less than that of TNBC MDA-MB-231 and MDA-MB-468 cell lines. The results presented here highlight the potential of a targeted …
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Bst2 Isoforms: Distribution and Potential Use In Cancer Therapeutics
… isoform in the malignant B-cell lines. Moreover, immunohistochemistry staining of ductal breast carcinoma tissues showed the ability of the generated MAb to detect long BST2-positive cancer cells surrounded by negatively stained normal tissue, indicating LA5 specificity for this isoform. In …
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Challenge studies in chickens to evaluate the efficacy of commercial Newcastle disease vaccines against the strains of Newcastle disease virus prevalent in South Africa since 2002
… vaccine and challenged with GPMV isolate, and immunohistochemistry staining used to determine the distribution pattern of viral antigen in the oviduct of the hens. The second study also compared the efficacy of cloacal and ocular routes of vaccination. The first study did not detect any …
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The analysis of genetic aberrations in South African oesophageal squamous cell carcinoma patients
… pro-inflammatory enriched pathways. Immunohistochemistry staining showed 10 out of 13 of the samples had no detectable levels of MUC3A protein, suggesting that the production of a non-functional truncated protein may lead to the upregulation of MUC3A expression that could possibly …
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Surface engineering, characterisation and applications of synthetic polymers for tissue engineering and regenerative medicine. Investigation of the response of MG63 osteosarcoma cell line to modified surface topographies, mechanical properties and cell-surface interactions using different synthetic polymers fabricated in house with various topographical features
… Imaging of MG-63 osteosarcoma cells using immunohistochemistry staining kits was conducted to observe the relationship between cell length and surface topography followed by a comparison between HaCaT (skin) cells and MG-63 (bone) cells. Following experimental testing mechanical variations …
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Epstein-Barr virus suppression in chronic obstructive pulmonary disease
… and stable disease using sputum qPCR and immunohistochemistry staining of airway biopsies. In this study we hypothesised that this herpesvirus could represent a novel therapeutic target in COPD. <br/><br/>Methods: The EViSCO trial was a single-centre, double-blind, randomised, …
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Prognostic biomarkers for head and neck squamous carcinoma
… RadSl, XRCC1, ERCC1 and HEP-la was tested using immunohistochemistry staining IHC. The tested genes were found to be expressed at varying levels in HNSCC patients. Associations between the level of the expression and gender, site of origin, tumour differentiation, TNM stage, lymph node …
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Pathological and Biomedical Characteristics of Spinal Cord Injury Determined Using Diffusion Tensor Imaging
Traumatic spinal cord injury: SCI) is the most devastating injury that often causes the victim permanent paralysis and undergo a lifetime of therapy and care. It is caused by a mechanical impact that ultimately causes pathophysiological consequences which at this moment in time are an unresolved …