Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Immunoglobulin E"”.
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Regulation of Human Monocyte Function by Cross-Linking of Immunoglobulin E
Cross-linking of IgE by allergen triggers many cellular processes that drive allergic disease. While the role of IgE in mediating allergic responses is best described on basophils and mast cells, expression of the high-affinity IgE receptor on other innate immune cells, including monocytes, …
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Studies investigating peripherial blood derived cells that express the high affinity receptor for immunoglobulin E (FceRI) in allergic disorders
… is just forty years since the identification of immunoglobulin E (IgE) as the reagin responsible for allergen induced immediate hypersensitivity reactions. IgE exerts its biological actions through the binding of its Fc fragment to specific Fc receptors on effector cells. There are two …
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Studies investigating peripheral blood derived cells that express the high affinity receptor for immunoglobulin E (Fc?RI) In Allergic Disorders
… is just forty years since the identification of immunoglobulin E (IgE) as the reagin responsible for allergen induced immediate hypersensitivity reactions. IgE exerts its biological actions through the binding of its Fc fragment to specific Fc receptors on effector cells. There are two …
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SYNTHESIS OF NANOCOMPOSITES BY LASER ABLATION
Immunoglobulin E (IgE)-conjugated gold nanoparticles were produced via in situ conjugation of gold nanoparticles with immunoglobulin E by laser ablation of Au in a liquid solution. The colloidal stability and the size distribution of the resulting bio-nanoconjugates were examined with UV-Visible …
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The role of IL-4Ra during acute schistosomiasis
… tissue cosinophilia and high levels of serum immunoglobulin E. It is postulated that in addition to egg specific CD4+T cells, an IL-4Rα+ non-T cell effector population is required to prevent tissue pathology. The role of this dissertation was to examine the functional role of IL-Rα expression …
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Genetic and environmental influences on cord blood atopic markers and on atopic sensitisation in infancy
… that a raised concentration of cord blood serum immunoglobulin E (CBsIgE) is an excellent predictive marker for the subsequent development of atopic disease. Other potential predictive atopic markers such as cord blood eosinophils, platelets and anti-cow's milk serum IgG have also been suggested …
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A Microfluidic Approach to Selection and Enrichment of Aptamers for Biomolecules and Cells
… of target-binding nucleic acids against human immunoglobulin E (IgE), the glucose-boronic acid complex, and MCF-7 cancer cells. With the physical and functional integration allowed by the monolithic design realized in our devices, the total process time for selection of aptamers was drastically …
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Frequency and predictors of tonsil surgery
… tobacco smoke, asthma, allergies, serum Immunoglobulin E level, high body mass index, middle ear infections, upper respiratory tract infections, Down syndrome, and prematurity. Using data from the UAE, our case study suggests that tonsil surgery is associated with nationality, maternal …
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Protein engineering and characterization of a stable trimeric form of CD23 and a fluorescent IgE biosensor
Immunoglobulin E (IgE) plays a critical role in allergic diseases such as asthma and atopic dermatitis. Cross-linking of IgE bound to its high affinity receptor, FceRI, by allergen on mast cells and basophils results in the release of inflammatory mediators and induces allergic reactions. IgE can …
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Infant neurodevelopment and parental psychosocial functioning in pediatric food protein-induced enterocolitis syndrome
… enterocolitis syndrome (FPIES) is a non-immunoglobulin-E-mediated food allergy characterized by severe gastrointestinal symptoms within hours of food trigger ingestion. FPIES typically presents in infancy, and some babies have multiple triggers that are difficult to identify, resulting in …
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The role of Interleukin-4 induced gene 1 (IL-4i1) in allergic asthma and atopic dermatitis
… are said to be induced by elevated levels of immunoglobulin E (IgE) and T helper 2 (Th2) immune cells and inflammatory associated cells such as eosinophils, mast, and basophils. Globally, asthma is affecting more than 300 million people and is characterized by chronic airway inflammation, …
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Evaluation of γ-Irradiated Peanut Extract as a Proper Immunogen for Immunotherapy in Murine Model of Peanut Allergy
… of the proteins. In addition, the use of immunoglobulin E (IgE) from peanut-hypersensitive patients allowed the changes in the allergenicity and antigenicity of irradiated proteins to be observed by PN specific IgE immunoblotting and competitive indirect enzyme-linked immunosorbent assay …
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Risk factors for work-related asthma in health workers with exposure to diverse cleaning agents in two African health care settings
… collected from 682 HWs and analysed for specific immunoglobulin E (sIgE) antibody reactivity to common aero-allergens (Phadiatop) and specific occupational allergens (NRL - Hevea brasiliensis (Hev b5, Hev b6.02), chlorhexidine and OPA). Methacholine challenge tests (MCT) were performed on all …
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Cloning, Expression, and Characterization of Ara h 3, a Major Peanut Allergen
<p>Abstract There are eight foods that contribute to food allergies in the western world and peanut is the most common. Currently, there are no medical treatments that can cure an individual of food allergy, so avoidance of the allergic food is the only option. In the United States, there are three …