Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 10 of 10 for “"Immunity, Cellular"”.
-
Mathematical modelling of autophagy pathway.
… plays an important role in physiological cellular processes, is a survival mechanism under external stress and is also connected with cancer and neurodegenerative diseases [Cuervo, 2004; Kondo et al., 2005; Levine, 2007; Pan et al., 2008]. Autophagy is the pathway for degradation of …
-
Defining How Polymorphisms at the Slam Family Locus Affect NK and T Cell Function
… in regulating several immune functions such as cellular activation, cytokine secretion, cytotoxicity, and apoptosis. Thus, it is not surprising that dysregulation of this family of receptors is associated with disease states such as systemic lupus erythematosus (SLE) and X-linked …
-
Dynamic Behaviors of Langerhans Cells In Situ
The file named "wardbrant.pdf" is the primary dissertation file. Supplemental videos (Movies 1-27) are also provided (in RealPlayer Video format), and more information about each video is available in the file named "Legend.pdf".
-
B and T Lymphocytes in Human Pregnancy
<p>The success of the fetus as a transplant has been attributed to an immune depression in the mother. It has not been shown whether this purported depression was due to fewer T-lymphocytes or a dysfunction of these cells. T cells were measured by the rosette technique using neuraminidase treated …
-
Effects of the Removal of Adherent and Phagocytic Cells on the Spleen Cell Lymphoproliferative Response of Tumor Bearing Mice
<p>Cell-mediated immunity was investigated in two BALB/c mouse tumor systems using the lymphocyte transformation test with phytohemagglutinin as the mitogen. This lymphoproliferative response was quantitated using the Stimulation Index (SI). Spleen cells from mice injected with #51 cells, a …
-
Effect of Time and Diet on the Immune Status of Mice Challenged with Herpes-transformed Cells
… <p>In the experiments dealing with the status of immunity with time after tumor cell injection, mice were fed Purina Laboratory Chow (P.L.C.), injected with H238 cells, and sacrificed three to eight weeks post-injection. In the diet experiments, groups of mice were fed either P.L.C. or one of six …
-
Hypochlorous Acid Mediated Damage of Chromatin
<p>Hypochlorous acid (HOCl), the primary product of activated neutrophils at sites of inflammation, can damage both DNA and associated histone proteins. HOCl damage to cytosine bases in DNA generates the chlorination damage products 5-chlorocytosine (ClC) and 5-chlorouracil (ClU) as well as the …
-
Mechanism of Chimeric Vaccine Mediated Immune Suppression of Human Dendritic Cells
… T cells to regulate the delicate balance between immunity and tolerance required to maintain immunological homeostasis. In this dissertation, immature human dendritic cells (iDC) were inoculated with a chimeric fusion protein vaccine containing the pancreatic β-cell auto-antigen proinsulin linked …
-
The Role of the Pituitary-Adrenal Axis in G-CSF Therapy after Neonatal Hypoxia-Ischemia
<p>Several reports indicate that the activity of the hypothalamic-pituitary-adrenal axis (HPA) as measured by the increased level of adrenocorticotropic hormone (ACTH), and corticosterone is increased after a brain insult. These hormones are the effectors secreted respectively by the pituitary and …
-
Cellular Responses in ESCHERICHIA COLI to Lethal and Sublethal Doses of Ozone
… without affecting cell viability. The intracellular components, protein and plasmid DNA, remained intact. The enzymes malate dehydrogenase, lactate dehydrogenase and glutathione disulfide reductase were unaffected, while glyceraldehyde-3-phosphate dehydrogenase activity decreased …