Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1099 for “"Immune responses"”.
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Melanocortin Peptides Coordinate Metabolic and Immune Responses
Pages 84-114 are misnumbered as pages 83-113.
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Antibody-Mediated Modulation of Polyclonal Immune Responses
… defense are sequentially activated: the innate immune response and the adaptive immune response. The innate immune response is the first line of defense, and consists mainly of myeloid cells that are quickly activated within hours to days to engage in a non-specific manner. This broad response …
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Host modulation of excessive innate immune responses
A fundamental role of the innate immune system is to elicit a proper response against both invading pathogens and tissue damage or danger signals. Although the innate immune system often is successful in eliminating danger, an excessive host-response can result in severe tissue injury. Factors that …
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Immunoglobin synthesis during the primary immune responses
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Immune responses to next generation computer gaming
… investigate stress (as measured by cortisol) and immune response (s-IgA was used as a marker) to step aerobics on the Nintendo Wii between people with varying degrees of cardiorespiratory fitness (fair and good). Measures were taken at baseline and then after participants had attended three 30 …
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Determinants of innate immune responses to mycobacteria
… granulocytes recognise mycobacteria and initiate immune responses such as phagocytosis, cytokine production and expression of maturation markers. The type and magnitude of innate responses to mycobacteria may determine the subsequent adaptive responses generated. Our aims were to determine …
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Modelling Multivariate Nonlinear Vaccine Induced Immune Responses
… models for multivariate vaccine induced immune response data are important as they provide a rigorous means of deciding which vaccine candidates should be advanced in the clinical trials process. We consider applications of several different statistical models to a vaccine data set which …
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Profiling B cell immune responses by microengraving
The ability to monitor an immune response in the course of vaccination or disease progression is highly desirable. Currently, no technique is able to generate a comprehensive profile of the individual cells involved and the antibodies they produce at a particular point during the immune response. …
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Profiling, prototyping, and perturbing human immune responses
… combinatorial chemical perturbation of human immune cells using droplet microfluidics. In addition, we apply this framework to identify immune phenotypes associated with sepsis and severe COVID-19, and develop an experimental system that models sepsis-induced emergency myelopoiesis using human …
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Modeling Host Immune Responses in Infectious Diseases
… people with suppressed and compromised immune systems are at higher risk of suffering from infectious diseases. In spite of significant advancements in infectious diseases research, the control or treatment process faces challenges. The mucosal immune system plays a crucial role in …
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Multigenic Regulation of the Shutdown of Immune Responses
… blocking cell death could affect the shutdown of immune responses by generating increased numbers of antigen-specific memory CD8+ T cells. During acute viral infection, large numbers of effector CD8+ T cells are generated. Following viral clearance, the majority of these cells undergo apoptosis …
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Innate and humoral immune responses to HIV-1
Understanding cellular and humoral immune responses to HIV-1 infection and designed HIV immunogens are imperative to the development of an effective anti-HIV vaccine. In this thesis we investigate aspects of both the cellular innate and adaptive humoral arms of the immune system in response to …
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Diversity of protective immune responses in human malaria
Contains fulltext : 230402.pdf (Publisher’s version ) (Open Access)
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Regulatory Immune Responses and Repair Mechanisms in Atherosclerosis
… is a complex disease where both autoimmune responses towards atherosclerosis-related antigens and smooth muscle repair responses play important roles. This thesis contains studies focusing on both regulatory immune responses and tissue repair mechanisms in experimental models of …
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Immune responses in primary and metastatic breast cancer
… disease remains incurable. The role of the immune system in breast cancer has been questioned for over 100 years and more recently has led to major developments most notably in the form of Herceptin. Current evidence suggests that the immune system is stimulated by tumours to manifest a …
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Modulation of immune responses by human paraininfluenza virus
… infections, a comprehensive study investigating immune responses to this respiratory pathogen was undertaken. A human ex vivo model of viral infection was developed. Priming by HPIV3 was compared to immune responses induced by influenza A virus, which unlike HPIV3 primes immunity to …
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Anti-vector immune responses to an MVA vaccine
This study characterised the humoral and cellular immune responses to MVA from a candidate MVA-vectored HIV vaccine in non-human primates, and examined the effect of anti-vector immunity on the response to the HIV immunogens.
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