Global ETD Search
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Showing 1 to 5 of 5 for “"Imidazopyridine"”.
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Development of biologically active metal complexes: synthesis, spectroscopy and biological evaluation of ruthenium-based benzimidazolium complexes against cancer
… on the synthesis and characterisation of ionic imidazopyridine tetracarboxylato diruthenium complexes bearing different counterions like NO3, PF6 and BF4. The complexes were fully characterized using a variety of analytical techniques such as spectroscopy (1H, UV-Vis and FTIR) and cyclic …
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Antimalarial benzimidazoles and related structures incorporating an intramolecular hydrogen bonding motif: medicinal chemistry and mechanistic studies
… two classes of compounds, benzimidazoles and imidazopyridines, incorporating an intramolecular hydrogen bonding (IMHB) motif, were explored for their antimalarial potential. These two chemotypes were selected on account of their privileged nature due to their capacity to interact with various …
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Design, synthesis, and structure-activity relationship studies of dual Plasmodium falciparum phosphatidylinositol 4-kinase and cGMP-dependent protein kinase inhibitors
… activity of an established anti-malarial imidazopyridine scaffold. Medicinal chemistry optimization strategies largely revolved around the incorporation of water solubilizing features (Figure 2). Thus, a series of phenyl carboxamides were appended on the left-hand side of the core scaffold …
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Development of Pd Catalyzed Amidations & Applications to the Synthesis of Heterocycles
<p>Chapter 1</p> <p>A brief overview of C-N amide bond formation: past methods and current catalytic approaches.</p> <p>Chapter 2</p> <p>A facile synthesis of imidazo[4,5-b]pyridines and -pyrazines is described using a Pd-catalyzed amide coupling reaction. This reaction provides quick access to …
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Design and synthesis of Push-pull chromophores for cell imaging and OPV devices [Progettazione e sintesi di cromofori Push-pull per l'imaging cellulare e i dispositivi OPV]
Questa tesi di dottorato si concentra sulla progettazione, sintesi e caratterizzazione di nuovi cromofori push-pull, sviluppati per due applicazioni avanzate: l’imaging cellulare e il fotovoltaico organico (OPV). Unificate dall’integrazione strategica di gruppi donatori-accettori nelle architetture …