Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Iloprost"”.
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Effects of iloprost on embryo development in vitro
… conditions. It has recently been reported that Iloprost, a biosynthetic prostacyclin analogue and cardiovascular active drug, enhances embryo development and prevents apoptosis. It is hypothesized that the mechanism involves the induction of the survivin pathway. In this study, growth patterns …
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The utilization of the prostacyclin analogue iloprost in the cryopreservation of stallion spermatozoa
… other three to be exposed to various levels of Iloprost (0.001 μg, 0.1 μg, and 1.0 μg). All samples were frozen using a mechanical controlled rate freezer. Semen was analyzed for standard parameters post thaw using a computer assisted semen analyzer at 0 hr, 3 hr, and 4 hr time points. …
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Cardiovascular events and mortality in systemic sclerosis: A study of the effect of Iloprost on these and on disease progression: The SSTEP Study (Systemic Sclerosis Trial of Events and Progression)
… The aim of the study was to assess whether oral Iloprost was more effective than placebo in reducing cardiovascular events and disease progression in SSc.<br/><br/>Methods<br/>Two hundred and sixteen patients with systemic sclerosis were recruited, between February 2002 and February 2005, at nine …
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New routes to enantioenriched substances through small organic molecules
… a good enantioselection. A key intermediate of Iloprost, a chemically stable and biologically active mimic of prostacyclin PGI2 is synthesized following a ‘green approach’. An example of simple optical resolution of this racemic intermediate involving the diastereoisomeric salt formation is …
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Characterization of the prostacyclinIP receptor system in the rat kidney: Implications for diabetic nephropathy
… In response to 24 hr and 4 day HG, CCP- and iloprost (ILP)-cAMP was attenuated in MG: immortalized and primary cultures, respectively. CCP-CAMP was also diminished by anisomycin, a MAPK activator. PGI2 synthesis is dependent on cyclooxygenase (COX) and PGI 2 synthase (PGIS). We show increased …
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Einfluß der endothelialen Autakoide NO und PGI2 auf die Permeabilität endothelialer Gap Junctions
… wird. Denn nicht nur das Prostacyclin Analogon Iloprost (1 µmol/L), sondern auch der Aktivator der Adenylatcyclase Forskolin (30 µmol/L), verbesserte die Ausbreitung des Farbstoffes signifikant . Schließlich zeigen die Ergebnisse auch, daß die beiden vom Endothel gebildeten Substanzen sich …