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Showing 1 to 20 of 226 for “"Iga"”.
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Biomarkers in IgA nephropathy
Contains fulltext : 140179.pdf (Publisher’s version ) (Open Access)
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Characterization of human IgA-inducing protein
… list of DC-derived factors effecting B cells is IgA-inducing protein (IGIP). Here we characterize production of IGIP by human DCs, and examine its capacity to induce IgA class switching and differentiation of naïve B cells in vitro. Monocyte derived DCs were cultured in vitro with TLR agonists …
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Host-Microbial Interactions that Modulate Luminal IgA
<p>IgA is the most abundant immunoglobulin produced in the body, most of which can be found at mucosal sites such as the intestine where it plays an important role at a critical intersection between the host immune system and the microbiota. In the work detailed here, I sought to investigate IgA …
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IgA Nephropathy study according to the Oxford Classification: IgA Nephropathy clinical-morphological correlations, disease progression and the effect of renoprotective therapy
Immuunoglobuliin A nefropaatia (IgAN) on kõige sagedasem glomerulonefriit maailmas. Diabeetilise nefropaatia kõrval on IgAN järgmine oluline nefroloogiavaldkonna probleem, kuna haigestuvad peamiselt noored inimesed ja aeglaselt progresseerudes tekib lõpp-staadiumi neerupuudulikkus ligikaudu pooltel …
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Untersuchung von cosmc-Mutationen bei Patienten mit IgA-Nephropathie
Altered IgA1 galactosylation is involved in the pathogenesis of IgA nephropathy (IgAN), the most common glomerulonephritis in the world. The galactosyltransferase core-1 beta3-galactosyltransferase-1 (C1GALT1) and its chaperone cosmc are specifically required for O-galactosylation of the IgA1 hinge …
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TFR Cells Suppress Gut Commensal-Specific IgA Via IL-10
Immunoglobulin A (IgA) is the predominant antibody (Ab) at mucosal surfaces, playing a critical role in intestinal defense and regulation of gut commensals. A large amount of IgAcoated gut commensals is generated via T cell-independent pathways. However, highaffinity, antigen-specific IgA Abs are …
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Untersuchung zur Spezifität von Autoantikörpern bei Patienten mit linearer IgA Dermatose
Die lineare IgA Dermatose (LAD) ist eine subepidermal blasenbildende Erkrankung, die durch IgA-Ablagerungen an der kutanen Basalmembran charakterisiert ist. Die IgA-Antikörper von LAD-Seren reagieren mit einem 97 kDa Protein, das aus der Epidermis extrahiert werden kann, und einem 120 kDa Protein, …
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The effects of soccer-specific intermittent exercise on salivary IgA responses
… Lower concentrations of salivary 19A (s-IgA) as a predominant immunoglobulin and component of saliva or a chronic deficiency in s-IgA have been associated with an increased frequency of URTI episodes. Previous studies of aerobic exercise have incorporated the performance of running or …
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The Effect of Dental Plaque Accumulation on Secretory IgA in Saliva
… accumulation , parotid and whole secretory IgA (S-IgA) concentrations and minute secretion rates of S-IgA over a six week period. Eighteen healthy, male freshmen dental students were instructed to refrain from oral hygiene care for six weeks. Accumulation of plaque on the teeth of the …
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A comparison of IgA antibody levels in caries-resistant and caries-susceptible children
… correlation between salivary immunoglobulin A (sIgA) antibody levels to Streptococcus mutans and caries resistance in adults. In the present study, an enzyme-linked immunosorbent assay (ELISA) was used to compare IgA antibody levels to S. mutans in saliva from 20 caries susceptible (DMFS greater …
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Untersuchungen zur Analyse der O-Glykosylierung des IgA1-Moleküls im Krankheitsbild der IgA-Nephropathie
… HAA from Helix aspersa and Jacalin towards IgA1 O-glycans were characterized in detail. The aim was to evaluate existing techniques for the detection of undergalactosylated IgA O-glycans in IgA nephropathy and to develop and analyse new detection methods. A set of serum samples from IgAN …
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Identification and evaluation of Limosilactobacillus reuteri as an inducer of neonatal IgA and autoimmunity
… on the induction of early endogenous neonatal IgA, and we evaluate Limosilactobacillus reuteri's characteristics as an inducer. Garnering attention for use a probiotic, L. reuteri has many proven health promoting benefits, such as IgA induction, but emerging evidence also links specific strains …
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