Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"IgM secretion"”.
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Examining the Role of Regulatory Lymphocytes in a Mouse Model of BCL1 Tumor Dormancy
… did not suppress the proliferation nor inhibit IgM secretion by the tumor cells. Interestingly, we then found that the BCL1 tumor cells shared features with regulatory B (Breg) cells. Like Treg cells, Breg cells also induce immune tolerance by suppressing effector T cells. The BCL1 tumor cells …
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The role of cell type-specific tumour necrosis factor in protective immunity against neurotuberculosis
… and also to reduce antigen response and B cells IgM secretion. Our data suggest that neurons as well as microglia/macrophages and neutrophils derived tumor necrosis factor have a very limited role in protective cerebral immune responses. In MT-TNF-/- mice, TNF mediated protective immunity against …
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Golgi Specificity and Development of Autoreactive B Cells
… immortalized as hybridomas show B cell receptor (IgM) accumulation in the Golgi. Receptor accumulates in the Golgi only when the heavy chain is paired with the Vk38c light chain. The location of B cell receptor accumulation in these hybridomas ranges from the <em>cis</em>-Golgi to medial- and …
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DISSECTING IMMUNE DYSREGULATION IN PATIENTS WITHTHYMIC EPITHELIAL TUMORS BY AUTOANTIBODY ANDSINGLE-CELL PROFILING
… with strong internal correlations. In contrast, IgM autoreactivity was reduced in AB and B thymomas yet increased in TH, consistent with sustained unswitched memory B cells and long-term IgM secretion. Together these findings support a model in which aberrant intratumoral thymopoiesis fails to …