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Showing 1 to 1 of 1 for “"IgH/c-myc translocation"”.
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The Role of Activation-Induced Cytidine Deaminase in Antibody Diversification and B Cell Malignancies
… an organism as it gives rise to antibodies of high affinity and avidity crucial in clearance of the antigen by humoral immune response. Aberrant AID activity, however, can lead to c-myc/IgH chromosomal translocations and ultimately to B cell lymphomas and plasmocytomas in mice. Such …