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Showing 1 to 20 of 199 for “"IgA"”.
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Biomarkers in IgA nephropathy
Contains fulltext : 140179.pdf (Publisher’s version ) (Open Access)
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Characterization of human IgA-inducing protein
… list of DC-derived factors effecting B cells is IgA-inducing protein (IGIP). Here we characterize production of IGIP by human DCs, and examine its capacity to induce IgA class switching and differentiation of naïve B cells in vitro. Monocyte derived DCs were cultured in vitro with TLR agonists …
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Host-Microbial Interactions that Modulate Luminal IgA
<p>IgA is the most abundant immunoglobulin produced in the body, most of which can be found at mucosal sites such as the intestine where it plays an important role at a critical intersection between the host immune system and the microbiota. In the work detailed here, I sought to investigate IgA …
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TFR Cells Suppress Gut Commensal-Specific IgA Via IL-10
Immunoglobulin A (IgA) is the predominant antibody (Ab) at mucosal surfaces, playing a critical role in intestinal defense and regulation of gut commensals. A large amount of IgAcoated gut commensals is generated via T cell-independent pathways. However, highaffinity, antigen-specific IgA Abs are …
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The effects of soccer-specific intermittent exercise on salivary IgA responses
… Lower concentrations of salivary 19A (s-IgA) as a predominant immunoglobulin and component of saliva or a chronic deficiency in s-IgA have been associated with an increased frequency of URTI episodes. Previous studies of aerobic exercise have incorporated the performance of running or …
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Untersuchung zur Spezifität von Autoantikörpern bei Patienten mit linearer IgA Dermatose
Die lineare IgA Dermatose (LAD) ist eine subepidermal blasenbildende Erkrankung, die durch IgA-Ablagerungen an der kutanen Basalmembran charakterisiert ist. Die IgA-Antikörper von LAD-Seren reagieren mit einem 97 kDa Protein, das aus der Epidermis extrahiert werden kann, und einem 120 kDa Protein, …
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The Effect of Dental Plaque Accumulation on Secretory IgA in Saliva
… accumulation , parotid and whole secretory IgA (S-IgA) concentrations and minute secretion rates of S-IgA over a six week period. Eighteen healthy, male freshmen dental students were instructed to refrain from oral hygiene care for six weeks. Accumulation of plaque on the teeth of the …
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A comparison of IgA antibody levels in caries-resistant and caries-susceptible children
… correlation between salivary immunoglobulin A (sIgA) antibody levels to Streptococcus mutans and caries resistance in adults. In the present study, an enzyme-linked immunosorbent assay (ELISA) was used to compare IgA antibody levels to S. mutans in saliva from 20 caries susceptible (DMFS greater …
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Identification and evaluation of Limosilactobacillus reuteri as an inducer of neonatal IgA and autoimmunity
… on the induction of early endogenous neonatal IgA, and we evaluate Limosilactobacillus reuteri's characteristics as an inducer. Garnering attention for use a probiotic, L. reuteri has many proven health promoting benefits, such as IgA induction, but emerging evidence also links specific strains …
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Celiac Test Assay Comparison: Bio-Rad Autoimmune EIA Anti-Tissue Transglutaminase (tTG) IgA and IgG Tests on the Inova Quanta-Lyser 240 vs. BioPlex 2200 Celiac IgA and IgG Kits for Use at a Large Reference Laboratory
<p>As awareness of Celiac disease grows, testing services offered by clinical laboratories must expand accordingly. Testing needs at large reference laboratories are especially impacted by this change due to their coverage of broad geographic range and diverse patient populations. For this reason, …
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Characterization, Stabilization and Formulation Design of IgG and Secretory IgA Monoclonal Antibody Candidates during Storage and Administration
… of classes of immunoglobulin molecules (IgG and IgA). In addition, the effect of specific classes of excipients and solution conditions are examined by using a wide variety of physicochemical and immunological binding analytical techniques. Specifically, the second and third chapters of the Ph.D. …
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