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Showing 1 to 3 of 3 for “"Ice recrystallization inhibition"”.
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Ice Recrystallization Inhibition as a Mechanism for Reducing Cryopreservation Injury in a Hematopoietic Stem Cell Model
… reduce the yields of viable functional cells. Ice recrystallization is a mechanism of cryopreservation injury, but is rarely addressd in strategies to optimize cell cryopreservation. The results from this thesis demonstrate an association between the potency of carbohydrate-mediated ice …
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The Rational Design and Use of Novel Small-Molecule Ice Recrystallization Inhibitors for the Cryopreservation of Hematopoietic Stem Cells and Red Blood Cells
… RBCs. DMSO and glycerol are unable to control ice recrystallization which is a major source of cellular injury during cryopreservation. Therefore, compounds with the ability to inhibit ice recrystallization could represent a new class of cryoprotectant with a novel mechanism of action. This …
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DEVELOPMENT OF NEW PEPTIDE-BASED NANOMATERIALS AS POTENTIAL TOOLS FOR CRYOPRESERVATION OF TISSUES AND ORGANS
… the freezing point of body fluids, control the ice crystal nucleation and inhibit their growth. In particular, the latter AFP property, the ice recrystallization inhibition (IRI), is highly desirable for new synthetic antifreeze materials as ice recrystallization during thawing is associated to …