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Showing 1 to 20 of 33 for “"IUGR"”.
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Aggressive Behavioral Phenotype in Intrauterine Growth Restricted (IUGR) Baboons Exposed to Moderate Nutrient Restriction Early in Development
… aggression and intrauterine growth restriction (IUGR), which can result from low maternal food intake during pregnancy. The main hypotheses of this study are [1] IUGR offspring demonstrate higher rates of aggressive behavior and [2] IUGR offspring attain higher ranks. Behavioral observations were …
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Muscle Growth and Development in Intrauterine Growth Restricted Pigs
… pigs exhibit the most severe naturally occurring IUGR and reduced postnatal muscle growth. The objectives of this research project were to: 1) determine muscle stem cell characteristics in IUGR pigs; 2) determine how intrauterine growth restriction alters protein deposition in skeletal muscle; 3) …
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Intrauterine growth restriction (IUGR) and birth outcomes in a cohort of HIV-infected pregnant women in Cape Town, South Africa
Background: Intrauterine growth restriction (IUGR) is a major contributory factor of perinatal morbidity and mortality. This suboptimal growth is associated with infants being small-for-gestational age. In addition to genetic and placental factors, maternal factors such as infection are also …
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Development in children born very preterm after intrauterine growth restriction with abnormal fetal blood flow
… of fetuses with intrauterine growth restriction (IUGR) with abnormal umbilical artery blood flow in the second trimester represents a clinical dilemma. So far, no evidence based management protocols are available adressing when to deliver these fetuses. The high risk of hypoxia and fetal death has …
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Human milk oligosaccharide supplementation did not affect gut development in the healthy neonatal piglet
Background: Intrauterine growth restricted (IUGR) is a category of infants that are born underweight for their gestational age due to nutrient deficiency in the womb. They are at a higher risk for a variety of health issues later in life, which can be exacerbated if the infant is not breast-fed. …
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Axis of placental ageing in adverse pregnancy outcomes
… fetal outcomes. Intrauterine growth restriction (IUGR) is defined as the inability of the fetus to reach normal growth potential within the uterus as a result of various genetic, environmental, or placental factors. Premature ageing of the placenta in pregnancy outcomes such as PE and IUGR is …
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Leptin and peroxisome proliferator activated receptor alpha: understanding their contribution towards normalising the programmed phenotype in the peripheral tissues of IUGR offspring
… a rat model of intrauterine growth restriction (IUGR) induced by maternal global undernutrition, adult offspring are obese with associated metabolic disturbances. These metabolic abnormalities are all augmented by feeding a high calorie postnatal diet and reversed by neonatal leptin treatment. …
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Investigating thyroid hormone transport and regulation in chorionic somatomammotropin RNAi models of intrauterine growth restricted pregnancies
… results in an intrauterine growth restricted (IUGR) phenotype in sheep. Abnormal levels of thyroid hormones (THs) 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4, thyroxine) and abnormal expression of placental deiodinase 2 and deiodinase 3 (DIO2/DIO3) mRNA have been …
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Placental angiogenesis and immune-privilege in normal and pathological pregnancies
… normal and in pregnancies complicated by PE and IUGR. Angiogenin was identified for the first time to be produced in a gestation dependent manner with significantly increased levels of expression and secretion in PE and IUGR. On the other hand, levels of VCAM-1 and its mRNA were decreased in a …
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The role of thyroid hormones in placental development and the importance of the thyroid hormone transporter MCT8
… Human intrauterine growth restriction (IUGR) is associated with malplacentation and reduced fetal circulating concentration of THs. The expression of the plasma membrane TH transporters MCT8, MCT10, LAT1, LAT2, OATP1A2 and OATP4A1 was characterised in human placental biopsies across …
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Magnesium Sulphate Neuroprophylaxis in Pregnancy with IUGR due to Hyperitensive Disease /// Невропрофилактика с магнезиев сулфат при бременности с ретардация на плода вследствие на хипертензивни заболявания
Прееклампсията и свързаното с нея забавяне на растежа на плода е билатерален процес, засягащ както майката така и плода в основата, на който е васкуларната плацентарна инсуфициенция. Каузалното лечение е раждането, най-често преждевременно и много често ятрогенно. Недоносеността и незрелостта са …
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Role of PABP4 in intrauterine growth restriction
… which exhibit intra-uterine growth restricted (IUGR) fetuses from e15.5, and an increased prevalence of late-gestational fetal death (akin to stillbirth). Stillbirth affects approximately 1 in 225 pregnancies in the UK, and IUGR is not only a major risk factor for stillbirth but also for …
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Fetal Cardiac Function and Venous Circulation - Experiences with Velocity Vector Imaging
… resulting in intrauterine growth restriction (IUGR) is a common complication of pregnany and severe IUGR, with ensuing fetal hypoxia is an important cause of perinatal mortality and morbidity. Doppler studies of fetal and maternal vessels are routinely used for fetal surveillance and …
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The Role of Oxytocin in Bovine Satellite Cell Proliferation and Differentiation
… studies in intrauterine growth restriction (IUGR) sheep, caloric restricted (CR) calves, tamoxifen (TAM) treated heifers, and bovine satellite cells (BSCs), respectively. In the in-vivo studies, we collected (1) longissimus dorsi muscle (LM) from IUGR sheep; (2) infraspinatus muscle (INF), …
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Trophoblast Retrieval And Isolation From The Cervix (tric) For Non-Invasive Prenatal Genetic Diagnosis And Prediction Of Abnormal Pregnancy Outcome
… (PE), and intra-uterine growth restriction (IUGR). EVT migration into the uterine wall is dependent on growth factors and cytokines that signal between maternal and fetal tissues. The epidermal growth factor (EGF) signaling system plays a significant role in trophoblast function. Using …
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The impact of placental SLC2A3 (GLUT-3) RNA interference on fetal growth and physiology at mid-gestation in sheep
… and intrauterine growth restriction (IUGR). It was our objective to use placenta-specific RNA interference (RNAi) to diminish SLC2A3, and determine the impact at mid- gestation (75 dGA) in sheep. The resulting pregnancies underwent a terminal surgery at 75 dGA. SLC2A3 RNAi resulted in …
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Role of Activated Macrophages and Pro-Inflammatory Cytokines in Placental Trophoblast Invasion and Fetal Outcome
… and intra-uterine growth restriction (IUGR), which are major causes of maternal and fetal morbidity and mortality. These pregnancy complications have also been linked to an increased presence of pro-inflammatory cytokine-secreting (activated) macrophages at the fetal-maternal interface. …
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Consumption of Endophyte Infected Fescue During Gestation in Beef Cows
… contributes to intra uterine growth restriction (IUGR), and this work proposed that fescue endophyte toxicity affects the gestating cow and fetus. Three studies were completed. In experiment 1, gestating cows grazed high or low endophyte fescue pastures during late gestation to determine if …
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Effects of dietary intervention on inflammation and intrauterine growth restriction in neonatal piglets
Intrauterine growth restriction (IUGR), a form of fetal malnutrition that leads to small for gestational age (SGA) infants, is a condition that affects 7.5 million children born worldwide. Infants affected by IUGR are more prone to lengthy hospital stays, repeated infections, and neurodevelopmental …
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An investigation of antenatal screening and management of syphilis in two districts in the North West Province
… labour, intra uterine growth restriction (IUGR), neonatal death and congenital syphilis in the newborn. This study was undertaken in the Potchefstroom and Wolmaranstad Districts of the North West Province and was aimed at contributing to reducing perinatal mortality and morbidity within …
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