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Showing 1 to 1 of 1 for “"ITGA"”.
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Targeting integrin alpha 5 and focal adhesion kinase to overcome azacitidine resistance in higher risk myelodysplastic syndromes
… in virtually all patients. Integrin alpha 5 (ITGA5) and integrin signalling have been identified as drivers of primary resistance. I investigated whether combining azacitidine with either an integrin alpha 5 blocking antibody or a focal adhesion kinase inhibitor could overcome azacitidine …