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Showing 1 to 4 of 4 for “"ISW1b"”.
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THE MECHANISMS OF ISW1A, ISW1B AND ISW2 CHROMATIN REMODELERS
… mechanism of nucleosomes by ISW1a. ISW1a and ISW1b share the same catalytic subunit, but in vivo they are localized at different locations and is also known to have different roles. This suggests that the accessory subunits play a very crucial role in determining the identity of each complex. …
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AN EXAMINATION OF THE DOMAIN ARCHITECTURE OF THE IOC2 AND IOC3 SUBUNITS OF THE ISW1 COMPLEXES IN SACCHAROMYCES CEREVISIAE
… to form two separate complexes, namely ISW1a and ISW1b. ISW1a is composed of Isw1 and Ioc3; ISW1b consist of Isw1, Ioc2 and Ioc4. While these complexes share the same catalytic subunit, these complexes differ in their catalytic properties and function in vivo. ISW1a was shown to be localized at …
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DISTINCT GENOME WIDE FUNCTIONS OF CHROMATIN REMODELERS IN NUCLEOSOME ORGANIZATION AND TRANSCRIPTION REGULATION
… subunit. All members of the ISWI family (ISW1a, ISW1b, ISW2) share a conserved C-terminal HAND, SANT and SLIDE domains, which are important for sensing linker DNA. We find an auto-regulation of ISWI complexes by the SLIDE domain, independent of the histone H4 Nterminal tail. Our protein-protein …
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MECHANISMS OF CHROMATIN REMODELING BY ISWI FAMILY OF REMODELERS: A FUNCTIONAL AND STRUCTURAL INSIGHT INTO THE ROLE OF THE Itc1 SUBUNIT OF ISW2 REMODELING COMPLEX
… analysis of the remodeling properties of ISW1a, ISW1b and ISW2 complexes with various nucleosomal substrates was done. The analysis revealed significant differences in substrate specificities and translocation mechanisms among these three remodelers. The most intriguing observation was that ISW1a …