Global ETD Search
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Showing 1 to 8 of 8 for “"ISRE"”.
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Sindbisvirus aktivierte ISRE-bindende Komplexe in L-929- Zellen
… Interferon(IFN)- stimulated- response- element (ISRE)- Bindungsproteine untersucht, welche in der transkriptionellen Induktion von IFN Typ I induzierter Gene beteiligt sind. Mittels Gelretentionsanalyse in der ein humanes Interferon-stimuliertes Gen 15 ( ISG15 ) Verwendung fand, wiesen wir in …
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ISRE-bindende Komplexe nach Sindbisinfektion in Mäuse- und Hühnerzellen
… Interferon(IFN)- stimulated- response- element (ISRE)- Bindungsproteine untersucht, welche in der transkriptionellen Induktion von IFN Typ I induzierter Gene beteiligt sind. Mittels Gelretentionsanalyse in der ein humanes Interferon-stimuliertes Gen 15 ( ISG15 ) Verwendung fand, wiesen wir in …
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Signal Transduction and Transcriptional Regulation in the Response to Type I Interferon
… interferon stimulated response element (ISRE) present in all ISGs, which is necessary and sufficient for transcriptional responsiveness to IFN. Three nuclear DNA-binding factors were identified that specifically bind the ISRE, one which was constitutive and two whose presence was …
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Biochemische Charakterisierung und physiologische Bedeutung eines neuen durch Typ I Interferon induzierten Gens
… drei Interferon-Stimulierte-Response-Elemente (ISRE) und mehrere GAS- (Gamma-Aktivierte-Sequenz) Motive identifiziert werden, deren Einfluss auf die Induzierbarkeit des IFRG28-Promotors mit Hilfe von Deletionskonstrukten in Reporergenassays untersucht wurde. Die Analyse ergab, dass die Aktivität …
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Biological Functions of Intracellular Hepatitis B e Antigen
… reduced interferon stimulated response element (ISRE) activity and expression of interferon stimulated genes (ISGs) upon interferon-alpha (IFN- α) stimulation. Furthermore, in line with this, RNA-seq analysis of ISG induction profile from IFN-α treated patients showed that HBeAg(+) patients …
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Development of an Interferon Bioassay and Primitive Endoderm Cell Lines to Study Lineage Specification During Early Bovine Embryogenesis
… A novel interferon stimulatory response element (ISRE)-reporter assay was created, and provides adequate quantification to measure IFNT. Additionally, it has a shorter completion time than previous bioassays, and does not require the use of a live virus. The second study describes the development …
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Gangliosides와 oxidized low density lipoprotein (oxLDL) 에 의한 신경교세포의 활성조절 및 그 기전에 대한 연구
… Induce Nuclear Factor Binding to GAS/ISRE Elements 19 2. Gangliosides Induce the Phosphorylation of STAT1 and STAT3 23 3. Gangliosides Induce Phosphorylation and Activation of JAK1 and JAK2 25 4. Gangliosides Stimulate STAT-responsive Inflammatory Gene Expression 28 5. AG490 Reduces …
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The Regulation of Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 2 (SHP-2) in Brain Microglia
… suppressed nuclear factor binding to GAS/ISRE sequences which regulate iNOS and COX-2 expressions. Curcumin markedly inhibited the phosphorylation of STAT1/3 as well as JAK1/2 in microglia activated with gangliosides, LPS, or IFN-γ. Curcumin inhibits the expression of …