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Showing 1 to 1 of 1 for “"IRTK phosphorylation"”.
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Submonomer Synthesis and Structure-activity Relationship Studies of Azapeptide Inhibitors of the Insulin Receptor Tyrosine Kinase
… of the Insulin Receptor Tyrosine Kinase (IRTK) domain.</p> <p>Overexpression or unregulated signal transduction of the IRTK has been associated with increased levels of gene expression and cell proliferation that are hallmarks of tumor progression. Thus, the inhibition of un-regulated …