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Showing 1 to 1 of 1 for “"IRE1, steroids"”.
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Ire1 regulates cyp11a1 transcription to mediate steroidogenesis in the ovary
… identified inositol-requiring enzyme 1 alpha (IRE1) as a mediator CYP11A1 transcription. IRE1 is an ER stress signal transducer, however an ER stress response is not induced in KGN cells by forskolin treatment. We hypothesize that IRE1 is necessary to mediate CYP11A1 transcription in response …