Global ETD Search
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Showing 1 to 2 of 2 for “"IP3R subtype"”.
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Contributions of type 2 IP3 receptors to intercellular adhesions and invasion of glioblastoma cells
… by inositol 1,4,5-trisphosphate receptors (IP3Rs), which mediate Ca2+ release from the endoplasmic reticulum. Mammals express three IP3R subtypes (IP3R1-3). I show that in glioblastoma cell lines, IP3R2 is the least abundant subtype (<5% of all IP3Rs), and that loss of IP3R2 selectively …
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High-resolution optical analyses of IP3-evoked Ca2+ signals
… express inositol 1,4,5-trisphosphate receptors (IP3R) that mediate Ca2+ release from the endoplasmic reticulum (ER) when they bind IP3 produced after activation of cell-surface receptors. Vertebrate genomes encode three closely related subtypes of IP3R (IP3R1-3). High-resolution optical analyses …