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Showing 1 to 4 of 4 for “"INTERVAL trial"”.
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Epidemiology of blood donor health in the context of increased frequency of donation: The INTERVAL trial
… safely give blood donations more frequently. The INTERVAL trial was a large pragmatic trial conducted to assess whether blood supply in the UK could be safely increased by reducing the interval between blood donations. A total of 45,263 UK blood donors (50% men and 50% women) were assigned to …
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Developing tailored approaches from multi-arm randomised trials with an application to blood donation
… by a large-scale, UK-based blood donation trial called INTERVAL. In INTERVAL, male donors were randomly assigned to 12-week, 10-week, and 8-week inter-donation intervals, and female donors to 16-week, 14-week, and 12-week inter-donation intervals. The outcomes of this trial include the …
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Epidemiological studies of whole blood donation in the UK: Donor safety and retention
… well as to define comparator populations for the INTERVAL trial and COMPARE study for the purpose of assessing the representativeness of these cohorts. Data from the INTERVAL trial (2012-16; N=45,000), a large, parallel group, pragmatic, individually randomised trial, embedded in the routine blood …
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Effects of blood donation and iron homeostasis on medium and long term cardiometabolic outcomes
… records; (ii) up to 40,000 blood donors from the INTERVAL trial, including data on ~30 million genetic variants, 6 iron biomarkers, 7 cardiometabolic markers and serial surveys; (iii) up to 890,000 participants from the UK Biobank and 4 external genetic consortia, with data on 21 cardiometabolic …