Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"INM"”.
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NUCLEAR ENVELOPE TRANSMEMBRANE PROTEIN DISTRIBUTION AND TRANSPORT STUDIED BY SINGLE-MOLECULE MICROSCOPY
… membrane (ONM) or the inner nuclear membrane (INM) play crucial roles in both nuclear structure and functions, including: genome architecture, epigenetics, transcription, splicing, DNA replication, nuclear structure, organization and positioning. Furthermore, numerous human diseases are …
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Evaluation of aircraft performance algorithms in Federal Aviation Administration's Integrated Noise Model
The Integrated Noise Model (INM) has been the Federal Aviation Administration's (FAA) standard tool since 1978 for determining the predicted noise impact in the vicinity of airports. A review of the aircraft performance algorithms in the INM was conducted and improved models for true airspeed, …
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Batch foaming of hot melt extruded excipient/disintegrant/API pharmaceutical formulations and the study of the effects of the resulting cellular structures on API dissolution
… Pharmaceutical Ingredient (API). Indomethacin (INM) is used as model API; Eudragit EPO (EPO) is used as polymer excipient; AcDiSol and Crospovidone (Cros) are used as two kinds of disintegrant. The main objectives are to gain an understanding of the resulting morphologies, as well as the impact …
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Characterisation of Nuclear EnvelopeAssociated Proteins (NEAP) in Arabidopsis thaliana
… nucleoplasmic side, the Inner Nuclear Membrane (INM) and on the cytoplasmic side, the Outer Nuclear Membrane. The NE allows communication between both compartments through Nuclear Pore Complexes and bridges the cytoskeleton to the nucleoskeleton through the LInker of Nucleoskeleton to …
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Novel plant nuclear envelope-associated coiled-coil proteins
… and/or chromatin-binding inner nuclear membrane (INM) proteins. The components of the metazoan lamina lack sequence homologues in plants. There is however evidence of a network of nuclear filamentous proteins underlying the NE. This study aims to characterise a novel family of NE-associated …
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Foaming of amorphous drug delivery systems prepared by hot melt mixing and extrusion
… API / polymer binary systems: Indomethacin (INM) with Soluplus (PVCap-PVAc-PEG); Carbamazepine (CBZ) with PVCap-PVAc-PEG; and INM with Eudragit EPO. Comprehensive characterization of these binary systems carried out by combining Differential Scanning Calorimetry, Fourier Transform Infrared …
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Distinct Roles for Dynein Regulatory Proteins NudE and NudEL in Brain Development
… termed interkinetic nuclear migration (INM), require forces acting upon the nucleus to drive upward (basal) and downward (apical) movement in the proliferative ventricular zone (VZ) of the brain. Research from our lab has identified dynein, along with LIS1, as being responsible for …
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Characterisation of the Arabidopsis mid-SUN proteins at the plant NE
… mCherry and not the inner nuclear membrane (INM) membrane marker AtSUN2. These results indicate that AtSUN3 and AtSUN4 localise to the ONM/perinuclear ER and not to the INM. Altogether, this work indicates that mid-SUNs have functional roles in addition to LINC complex formation based on …
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Development of hot-melt extrusion as a novel technique for the formulation of oral solid dosage forms
… APIs processed by HME. Indomethacin (INM) and famotidine (FMT) were selected as model active substances while polyvinyl caprolactam graft copolymer, Soluplus® (SOL) and vinylpyrrolidone-vinyl acetate copolymer grades Kollidon® VA64 (VA64) and Plasdone® S630 (S630) were used as …
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Hypersonic phononic crystals
Manipulation of the distribution of phonons inM a solid is important for both basic science and applications ranging from heat management to reduction of noise in electronic circuits and creating materials with superior acoustic and acousto-optical properties. This thesis explores hypersonic …
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A putative interaction between mitochondrial cytochrome c oxidase subunit II (COX II) to lamin A/C and LAP2α in colon epithelial cells.
… found underneath the inner nuclear membrane (INM). In mammals, Lamins are type V intermediate filaments. Three genes encode seven different lamin proteins. These genes are LMNA, LMNB1 and LMNB2. Lamins are classified into A- and B-types. A-type lamins, Lamin A, Lamin C, Lamin Aδ10 and Lamin …
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Charakterisierung der Kernmembranproteine Lamin-B-Rezeptor und Bocksbeutel von Drosophila melanogaster
Funktionelle Charakterisierung neuer Proteine der inneren Kernmembran von Drosophila melanogaster: Drosophila Lamin B Rezeptor (dLBR), ein integrales Membranprotein der inneren Kernmembran; Bocksbeutel alpha und Bocksbeutel beta, LEM-Domänen Proteine sowie deren potentiellen Interaktionspartner …