Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"ILC1"”.
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Innate memory to bacterial infection
The innate lymphoid cells (ILCs) ILC1, ILC2, and ILC3, which also includes the natural killer (NK) cells are important regulators and first line responder during pathogen invasion. The role of ILCs was evaluated using FACS sorting, cytokine production and surface markers analysis, cell depletion, …
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Identification of novel regulators of lymphocyte development and differentiation using CRISPR-Cas9 screens
… gRNA libraries prior to differentiation into ILC1, ILC2 and ILC3 subsets in an in vitro co-culture system. Using IL-13 expression as a readout, Nfkb2, Mef2d, Zfp871 and ADNP were identified and validated as novel regulators of CLP to ILC2 development and differentiation. Furthermore, screens …
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Molecular definition of group 1 innate lymphoid cells in the uterus
… conventional NK cells (cNK) and CD49a+Eomes- ILC1 has been unknown. Determining the function of uterine lymphocytes is challenging because of the rapidly changing nature of the organ in response to sex hormones and, during pregnancy, to the invading fetal trophoblast cells. In my work, I …
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Innate Lymphoid Cell Characterization and Ilc2S In Neuroinflammation In Aging and Sex Differences
<p>Aging affects immunologic responses by a global immune system suppression, including dysregulation of cytokine mediators, leading to increased inflammation throughout all systems, termed inflammaging. However, understanding healthy aging mechanisms can bypass this effect. Inflammaging also leads …