Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"IL5"”.
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Type I Interferon Mediates Th2 Reprogramming and Acute Suppression of Effector Functions
… the TCR-mediated expression of the human IL5 gene. IFN-α treatment potently suppressed IL5 and IL13 gene expression by reducing the rate of nascent transcription, independent of de novo expression of ISGs. Further, I show that IFN-α-mediated STAT4 activation is required to suppress gene …
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Molecular genetic mechanisms of eosinophil activation in aspirin-exacerbated respiratory disease : Genetic mechanisms of eosinophil activation
… specific receptor subunit IL-5 receptor alpha (IL5RA) have been attractive targets for eosinophil associated disorders. Furthermore, it has been reported that platelets interacted with eosinophils involve in both asthma and AERD patients, in which both cells could express purinergic receptor …
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Einfluss atopischer Prädisposition auf allergenspezifische Proliferation und Zytokinprofile maternaler und fetaler mononukleärer Blutzellen
… verwandt, mittels ELISA bestimmt wurden: IL4, IL5, IL10, IL13, IFNg. ERGEBNISSE: Angegeben werden jeweils die positiven Proliferationsantworten in Prozent (SI > 2) und der Stimulationsindex (SI): IL2: M 100 (21), N 100 (26); BLG: M 98 (14), N 92 (17); OVA: M 36 (2), N 31 (2); Derp: M 32 (2), N …
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Exacerbation and glucocorticoid toxicity profile in patients receiving mepolizumab for severe eosinophilic asthma
… severe eosinophilic asthma treated with anti-IL5 monoclonal antibodies?<br/><br/>2. To quantify toxicity associated with OCS treatment in severe eosinophilic asthmatics, and assess change in OCS-related toxicity after 1 year's treatment with mepolizumab and subsequent reduction in OCS, both …
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Die Funktion von intrazerebralen Makrophagen beim Staphylococcus aureus- induzierten Hirnabszess im Kontext der IL-4R-abhängigen Aktivierung
… Herabregulation der TH2-Zytokine Il13 und Il5, sowie der profibrotischen Mediatoren Il10, Tgfb1 und Ccl17. Diese führte morphologisch zwar zu einer alterierten M2-Antwort und Fibrosereaktion, dennoch konnte eine Expression der charakteristischen Marker und eine konsekutive Kapselbildung im …