Global ETD Search
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Showing 1 to 1 of 1 for “"IL37"”.
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From Phenotype to Genotype: Discovery of New Molecular Primary Immunodeficiencies
… bowel disease associated with a rare homozygous IL37 mutation. Functional validation using cell lines and induced pluripotent stem cells (iPSCs) revealed a failure of the mutant IL-37 to be secreted extracellularly or translocated to the nucleus causing an inability to suppress pro-inflammatory …