Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"IL-2 signalling"”.
-
The role of JAK1 and JAK3 in CD8<sup>+</sup> effector T cells
… the tyrosine kinases JAK1 and JAK3 in cytokine signalling, focusing on interleukin-2 signalling in CD8<sup>+</sup> effector T lymphocytes. Initial experiments compared the effects of the pan JAK1/JAK3 inhibitor tofacitinib, the selective JAK1 inhibitor GSK186, and the selective JAK3 inhibitor …
-
Identification and analysis of Il-2 induced Stat5 Target genes in Human CD4 and CD8 T cells
… of transcription (STAT) 5a and 5b, are key signalling<br/>proteins activated by the cytokine interleukin-2 (IL-2), and therefore critically regulates<br/>important immunological processes such as T cell homeostasis and immune-regulation.<br/>While the biological functions of STAT5 are well …