Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"IL-1: Interleukin-1"”.
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An investigation of the activation of protein kinase complexes in the MyD88 signalling network
… by which they are activated in this system are still unclear. In this thesis, I present the research I have carried out to solve these problems. <br/>The IKKb component of the canonical IKK complex is required to activate the transcription factors NF-kB and IRF5 and the protein kinase Tpl2, but …
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Vitamin D and Immunomodulation in Bronchial Asthma
… including TNF-α (Tumour Necrosis Factor-α), IL-1(Interleukin-1), IL-6(Interleukin-6), IL-8(Interleukin-8),and Transforming Growth Factor-β (TGF-β). Airway Smooth Muscle Cells (ASMCs) when activated in an antigen sensitized state, behave in an autocrine and paracrine manner by producing and …
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Protective Role of Mesenchymal MyD88 Signaling Under Homeostasis and Initiation of Inflammation in the Colon
… the immunopathogenesis of IBD, we used Lactobacillus rhamnosus GG (LbGG) as a representative species of normal beneficial gut microbiota. I demonstrated that mesenchymal stromal cells isolated from the normal human colonic mucosa responded to LbGG with activation of the eicosanoid pathway …