Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"IKZF1"”.
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IKAROS and LEUKEMIA
… 191 successfully analyzed cases, deletions of IKZF1 (∆IKZF1) and SPRED1 were shown to be associated with a poor prognosis, with ∆IKZF1 being an independent risk factor for relapse. To ascertain whether ∆IKZF1 is an independent risk factor also in the context of minimal residual disease (MRD) …
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Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia
… <em>E2A</em>), <em>EBF1</em>, <em>LEF1</em>, <em>IKZF1</em> (IKAROS), and <em>IKZF3</em>(AIOLOS). These findings suggest that direct disruption of pathways controlling B-cell development and differentiation contributes to B-progenitor ALL pathogenesis. Moreover, these data demonstrate the power of …
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Investigation of the anticancer activity and mechanisms of zinc diethyldithiocarbamate in multiple myeloma
… the mRNA expression of cereblon (CRBN), Ikaros (IKZF1), aiolos (IKZF3) and Interferon regulatory factor-4 (IRF4), a significant downregulation of protein levels was observed after treating the MM cell lines with sub-cytotoxic concentrations of ZnDDC (2-5 μM). After exposure to low concentration …