Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"IKS"”.
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Characterization of cardiac IKs channel gating using voltage clamp fluorometry
… the slowly activating delayed rectifier current, IKs. This current plays a major role in repolarization of the cardiac action potential, evidenced in part by its major role in shortening the action potential in the face sympathetic stimulation, which leads to phosphorylation-induced increase in …
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Electrostatic Interactions in the Voltage Sensor of Kv7.1 and Iks Channels
… including the heart and the brain. In the heart, IKs potassium channels generate an important repolarizing cardiac current that contributes to the termination of the cardiac action potential. Congenital mutations that disrupt the function of IKs can lead to cardiac arrhythmias and sudden death. …
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Functional and Biochemical Characterization of KCNQ1/KCNE1 Subunit Interactions in the Cardiac IKs Potassium Channel
The IKs potassium channel, critical to control of heart electrical activity, requires assembly of pore-forming alpha subunits (KCNQ1) and accessory beta (KCNE1) subunits. IKs is the slowly activating component of delayed rectifier K+ current in the heart and is a major contributor to the timing of …
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Computational Studies of the Concealed Gating Pathways and Electrophysiological Function of the Human Cardiac IKs Channel
… molecular processes of ion-channel gating using IKs as a paradigm. The simulations reproduce experimentally recorded saturation of gating charge displacement at positive membrane voltages, two-step voltage sensor movement shown by fluorescence, ion-channel statistics, and …
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Examining South Africa 's process of cultural transformation : interrogating the Indigenous Knowledge System (IKS) policy framework
Includes bibliographical references (leaves 91-104).
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Die ß-Untereinheit minK verändert die Reaktion des menschlichen Kaliumkanals KvLQT1 auf Änderungen des zytosolischen pH, seine Temperaturempfindlichkeit und seine Empfindlichkeit für Pharmaka
… Unterschiede zwischen den Strömen IKv und IKs beschrieben, die durch diese Kanäle geleitet werden. Die Assoziation mit dem minK-Protein führt sowohl zu Veränderungen der biophysikalischen Eigenschaften, wie der Spannungsabhängigkeit und der Aktivierungskinetik des Stromes, als auch zu einer …
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Hubungan antara kontrol diri dengan agresivitas pada anggota pencak silat: Study pada PSHT dan IKS PI Kera Sakti Bojonegoro
INDONESIA: PSHT dan IKS PI Kera Sakti adalah dua organisasi/perguruan pencak silat yang berada dibawah naungan Ikatan Pencak Silat Indonesia (IPSI). Kedua organisasi pencak silat ini sama-sama memiliki ajaran yang baik dan berbudi luhur yang seharusnya diaplikasikan untuk kehidupan sehari-hari …
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An exploration of the use of social media as a vehicle to enculturate Vhavenda youth in the Vhembe District, Limpopo Province of South Africa
… youth with the indigenous knowledge system (IKS). IKS mainly relies on information being passed on by word-of-mouth from adults; hence, it requires direct interactions between the older and younger generations. Social media have taken over the socialisation role played by older adults; …
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Effects of an argumentation-based instruction on grade 10 learners' understanding of the causes of pollution at a river site
… and Indigenous Knowledge Systems Project (SIKSP) at the School of Science and Mathematics Education, University of the Western Cape. The project seeks to enhance educators' understanding of and ability to implement a Science-IKS curriculum (Ogunniyi, 2007) through using the theoretical …
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Investigating Indigenous Knowledge Systems in the conservation of protected areas in KwaZulu-Natal, South Africa and Portland, Jamaica: policy, practice and management
… investigate Indigenous Knowledge Systems (IKS) in the conservation of Protected Areas in KwaZulu-Natal, South Africa and Portland, Jamaica. The aim of this study was achieved through the following objectives: (a) to identify and classify the IKS that exist in the study areas, (b) to …
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Exploring the decolonisation of the Environmental Management Curriculum in a Rural Historically Disadvantaged Institution of Higher Education
… consideration is Eurocentric because it excludes IKS. In addition, the study findings suggest that both academics and students have identified gaps and/or limitations in the current Environmental Management curriculum because its locus of enunciation is not Africa and South Africa. This is the …
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Design and Democracy: Transformative Agency within Indigenous Structure
… further research - Indigenous Knowledge Systems (IKS) and cosmopolitanism. The African concept of Ubuntu, a subset of IKS, is argued to function as an authentic context, however, its ability to influence urban and diverse environments is questioned. Cosmopolitan theory, and Dewey's focus on …
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Boundarywalkers: conceptualizing the dynamics of equitable science between Indigneous and Western knowledge
… knowledge systems, Indigenous Knowledge Systems (IKS) and Western Science Knowledge Systems (WSKS) can cogenerate knowledge. Interviewees for this study, as primary sources, contributed to the construction of a new concept, the boundarywalker framework, that conceptualizes the dynamics of …
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The classroom implementation of indigenous knowledge in the science curriculum by science teachers in the Western Cape province, South Africa
… critical role of Indigenous Knowledge Systems (IKS) in science education. These policy documents expect the science teachers to integrate indigenous knowledge in their lessons. This study strove to establish how selected high school science teachers in the Western Cape Province responded to the …
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Ubwinga, a subset of Bemba indigenous knowledge systems : a comparative study of pre-colonial and post-independence wedding ceremonies in Lusaka and Kitwe, Zambia
… investigated the nature and existence of Bemba IKS. This study employed qualitative research methods involving extensive fieldwork in Lusaka and the Copperbelt. Apart from audio-visual recordings and analysing 25 marriage ceremonies, individual and focus group interviews were conducted with …
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Participatory evaluation of the Bachelor of Indigenous Knowledge System at the University of Venda
… research participants included BIKS (Bachelor of Indigenous knowledge System) students, lecturers, indigenous knowledge system holders and IKS ( Indigenous Knowledge Knowledge) Coordinator. The findings of the study highlighted that the strength of the curriculum lies in its …
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Investigating African indigenoues knowledge strategies to mitigate gender-based violence: a case study of Bushbuckridge Municipality, in Mpumalanga Province of South Africa
… focusing on – 7 traditional leaders, 7 IKS knowledge holders and 7 specific relevant members of the public affected by gender-based violence. Data was collected through semi-structured interviews and focus-group discussions. Among the recommendations of this study is that the indigenous …
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Exploring the development of communication strategies for Indigeneous Knowledge -based agricultural produce in Tshidzivhe Village, in Thulamela Municipality of Limpopo Province, in South Africa
… deliberate partnerships and nurturing of the IKS produce ecosystem.
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A context-aware collaborative decision making framework for combating terrorism in Africa
… and further, Information and knowledge sharing (IKS) was found to influence Optimal/effective CDM (OCDM). Of the three pillars of institutional theory, the regulative pillar offered more insights on issues related to rules, discourse and practice and hence the challenges of OCDM attainment. …
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Assessing the impacts of climate change and adaptation strategies on smallholder farming in the Vhembe District, South Africa
… climate change impacts, adaptation and IKS based strategies to deal with climatic shocks. Focus group discussions (FGDs), semi-structured interviews with the extension officers elicited thematic data that complemented the interview survey. Climate data were obtained from the South Africa …