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Showing 1 to 9 of 9 for “"IGRA"”.
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Diagnóstico de la infección tuberculosa latente mediante IGRA (interferon gamma release assays) en Asturias
Los ensayos basados en la liberación de IFN-γ (IGRA) detectan la respuesta de los linfocitos T frente a los antígenos ESAT-6 y CFP-10 que expresa M. tuberculosis y están ausentes en M bovis BCG y en la mayoría de las micobacterias ambientales. Existen dos técnicas comerciales: QuantiFERON®-TB Gold …
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Characterisation of a public T cell clonotype enriched in m.tb infected individuals who do not progress to tuberculosis
… if healthy, M.tb infected individuals (i.e. IGRA+) have higher frequencies of kiif.tb expressing T cells compared to healthy uninfected individuals (i.e. IGRA-) or individuals with active TB. We also aimed to identify cost-effective methods for detecting kiif.tb T cells in peripheral blood …
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The role of antibodies in tuberculosis
… with negative interferon gamma release assay (IGRA) tests. However, greater levels of M.tb-specific IgG associates with IGRA conversion. Thirdly, I showed the development of flow cytometric assays to study opsonization and antibody dependant cellular phagocytosis (ADCP) of live mycobacteria in …
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A study to evaluate immunodiagnostic tests for tuberculosis infection and determinants of TB infection in a population of health care workers in the Western Cape of South Africa
… emergence of interferon - gamma release assays (IGRAs) for the diagnosis of LTBI, presents an opportunity for improved estimation of TB infection prevalence and incidence. Their utility in settings with high background prevalence TB and HIV infection is unknown. Major aims of the study were to: * …
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Characterisation of T cell specificity, functional, activation and memory profiles associated with QuantiFERON TB Gold conversion and reversion
… skin test (TST) and/or IFN--release assay [IGRA e.g. QuantiFERON TB GOLD (QFT)], is commonly thought to be a chronic state. However, longitudinal studies have demonstrated the dynamic nature of M.tb infection, whereby TSTs and IGRAs revert from a positive to a negative test in some …
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Tuberculosis treatment delay in adults and household transmission to children: a community-based study in a setting with high burden of tuberculosis and HIV
… [TST] and two interferon-gamma release assays [IGRA]) and disease. Total treatment delay was measured in adult TB source cases as the time from cough onset until treatment initiation, with those reporting no cough serving as the reference category. Logistic regression models were used to …
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Creating a Marked Mycobacterium avium subsp. paratuberculosis Vaccine Strain and Detecting Marker-Specific Immune Responses in Calves
… using an interferon gamma release assay (IGRA) and enzyme-linked immunosorbent assay (ELISA), respectively. Marker-specific IFN- release was measured by stimulating whole blood with marker peptides and proteins, while antibody response was assessed by incubating serum with the same marker …
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Elementary Preservice Teachers' Conceptions of and Reflections on Student Autonomous Problem-Solving and Mathematical Practices
… or approximation of practice (Grossman, Compton, Igra, Ronfeldt, Shahan, & Williamson, 2009a) centered around teaching; such as the camp experience, talking with teachers or their peers, the university coursework, or working with students. However, other lived experiences such as babysitting, …
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Model učenja logistike zasnovan na edukativnim igrama
… modela učenja logistike i SCM zasnovanog na igrama, čiji je jedan od ključnih elemenata originalni alat za podršku odlučivanju za izbor logističkih i SCM igara. Dodatni ciljevi koji se izdvajaju su razvoj novog modela kompetencija menadžera logistike i lanca snabdevanja i istraživanje …