Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"IFN-lambda"”.
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Modulators of Innate Gut Immunity to Enteric Viral Infections: Murine Norovirus (MNV) as a Model
… also able to identify a specific defect in the IFN-Lambda response of aged IECs. Furthermore, using the model of MNV infection to investigate the role of AhR signalling, the data I generated suggested a direct link between constitutive AhR signalling and innate interferon-mediated responses. …
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Roles of Interferon Lambda on Hepatitis B Virus Replication
… major cause of liver disease. Only interferon-α (IFN-α) and the nucleosidic inhibitors of the viral polymerase, lamivudine and adefovir, are approved for therapy. However, these therapies are limited by the side effects of interferon and by the substantial resistance of the virus to nucleosidic …
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The Effect of Endocytosis of Interferon-lambda and The Genotype of IL-10RB on The Cellular Responses to Cytokines
… II 관련에 의해 endocytosis 경로가 세분화된다. Interferon (IFN)은 type I, type II, 그리고 type III의 세 그룹으로 분류되며, Interferon lambda는 IFN-1, IFN-2, IFN-3로 다시 나누어지고 최근에 type III로 분류되면서 새로운 사이토카인으로 보고 되었다. IFN의 endocytosis에 대한 연구에서, IFN- 는 clathrin-dependent pathway를 이용하며, IFN-는 clathrin-/ caveolae-dependent …