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Showing 1 to 1 of 1 for “"IFN-γ immunity"”.

  1. Human Inborn Errors of Immunity: Tuberculosis, Autoimmunity, and Beyond

    … Mycobacterial Disease (MSMD), demonstrated that IFN-γ is indispensable for antimycobacterial immunity in humans.Moreover, homozygosity for a common missense mutation P1104A in a protein TYK2 was discovered as the first genetic predisposing factor to TB in humans. TYK2 P1104A selectively impairs …

    rockefeller Repository record for Human Inborn Errors of Immunity: Tuberculosis, Autoimmunity, and Beyond (opens in a new tab)