Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"IDH1 R132H mutation"”.
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RAPID DETECTION OF THE IDH1 R132H MUTATION IN GLIOMAS USING RECOMBINASE POLYMERASE AMPLIFICATION
… developed an assay to improve diagnosis of the IDH1-R132H mutation. Diagnosis guided resections has potential to extend life expectancy up to 10 years. Our assay identifies the status of the IDH1-R132H mutation which has a characteristic of slower growth. Surgery requires a delicate balance …
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Quantitative dynamics of T-cell receptor repertoires and their use for cancer patient stratification
… use for patient stratification based on their mutational status for the hotspot mutation IDH1 R132H in glioma. First, in Chapter 2 we deeply characterised the statistical properties of data generated from TCR repertoire sequencing, in order to understand the source and amount of expected …