Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"ID proteins"”.
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The Role of Id Proteins in the Development and Function of T and B Lymphocytes
<p>E and Id proteins are members of the basic helix-loop-helix (bHLH) transcription regulator family. These proteins control a broad range of lymphocyte biology, from the development of multiple lineages to execution of their effector functions. With the development of new experiment models, novel …
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Structural characterization and biochemical analysis of ID2, an inhibitor of DNA binding
The ID proteins, a class of transcription regulators, were named for their role as inhibitors of DNA-binding and differentiation. They contained a helix-loop-helix (HLH) domain without a basic DNA-binding domain and functioned through dimerization with basic-HLH transcription factors to inactivate …
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The role of Inhibitors of Differentiation proteins ID1 and ID3 in breast cancer metastasis
… this disease. The Inhibitor of Differentiation proteins 1 and 3 (ID1/3) are transcriptional regulators that control many cell fate and developmental processes and are often deregulated in cancer. Our group and others have previously demonstrated that ID1/3 are required and sufficient for the …