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Showing 1 to 1 of 1 for “"ICUE3 cAMP reporter"”.
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Rotational motion and organization studies of cell membrane proteins
… and an increase in intracellular cyclic AMP (cAMP). ICUE3 is an Epac-based cAMP sensor with two fluorophores, cyan fluorescent protein (CFP) and the YFP variant, cpVenus, and a membrane-targeting motif which can be palmitoylated. Upon binding cAMP, ICUE3 undergoes a conformational change that …