Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"ICSS"”.
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EFFECTS OF MU OPIOID RECEPTOR AGONISTS ON INTRACRANIAL SELF-STIMULATION IN THE ABSENCE AND PRESENCE OF “PAIN” IN RATS
… abuse liability. Intracranial self-stimulation (ICSS) is a preclinical behavioral procedure that has been used to assess abuse potential of opioids, and drug-induced facilitation of ICSS is interpreted as an abuse-related effect. ICSS can also be used as a behavioral baseline to detect affective …
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Cannabinoid Modulation of Reinforcement Maintained by Stimulation of the Medial Forebrain Bundle in C57Bl/6J Mice
… cannabinoids is intracranial self-stimulation (ICSS), where an animal performs a response to receive electrical stimulation of a specific brain area or circuit known to be involved in reward. Drugs of abuse, such as psychomotor stimulants, facilitate responding for ICSS. While a few studies have …
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Electrical stimulation of reward sites in the ventral tegmental area of the rat increases dopamine transmission in the nucleus accumbens as measured by in vivo microdialysis
… that supported intracranial self-stimulation (ICSS). In the first experiment, both ICSS and yoked-stimulation of the VTA evoked significant increases in extracellular concentrations of DA, its metabolites, and 5-HIAA.Comparable results from ICSS and yoked groups were interpreted as evidence …
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Counselor Educator's Perspective on Clinical Supervision Interventions for International Counseling Students
… of international counseling students (ICSs). Based on the review of current clinical supervision literature, the researcher created a Q sort that addresses what ICSs believe as helpful or could have been helpful supervision interventions on improving their professional development. The …
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Effect of cannabinoids on pain-stimulated and pain-depressed behavior in rats
… or depress intracranial self-stimulation (ICSS) (pain-depressed behavior), whereas, IP injection(s) of lipopolysaccharide (LPS) served as a chronic/acute inflammatory-related noxious stimulus to stimulate mechanical allodynia (pain-stimulated behavior) or depress ICSS (pain-depressed …
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Trusted Software Updates for Secure Enclaves in Industrial Control Systems
Industrial Control Systems (ICSs) manage critical infrastructures such as water treatment facilities, petroleum refineries, and power plants. ICSs are networked through Information Technology (IT) infrastructure for remote monitoring and control of physical processes. As ICSs integrate with IT …
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Determinants of Abuse-Related Effects of Monoamine Releasers in Rats
… assays in rats: intracranial self-stimulation (ICSS) and drug discrimination. First, this work confirmed and expanded upon previous findings that selectivity for promoting release of dopamine versus serotonin is one determinant of abuse-related effects produced by monoamine releasers. This was …
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Managed Anomaly Detection for Industrial Control Systems
… requires connecting Industrial Control Systems (ICSs) to the Internet; however, combined with historically insecure protocols and increasingly sophisticated threat actors, this makes ICSs a prime target for cyberattacks. Anomaly detection is a promising countermeasure which aims to detect attacks …
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A Case Study for Cyber Incident Report in Industrial Control Systems
… for political gain. Industrial Control Systems (ICSs) have been used in critical infrastructure sectors such as nuclear reactors for power generation. These ICSs have evolved to connect with the enterprise systems for centralized management, opening up new risks. The risks of ICS Cyber Incidents …
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Shuttlebox Self-Stimulation Behavior Following Intracerebral Microinjections of Morphine Into the Ventral Tegmental-Substantia.
… effects on intracranial self-stimulation (ICSS). The present study attempted to replicate the reward-enhancing effects of morphine injected into the VT-SN area using the shuttlebox paradigm, a rate-independent measure of reward facilitation. It was found that 5 μg morphine injected into …
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Algorithms for Reconstructing and Reasoning about Chemical Reaction Networks
… infer the instability causing structures (ICSs) of a CRN and use machine learning techniques to relate properties of the CRN to the presence of such ICSs. This work has the potential to aid in not just network comprehension but also model simplification, by helping reduce the complexity of …
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Implementation of a Testbed with SDN-enabled Communication Networks to Experiment on Physical Function Virtualization that Disrupts Reconnaissance of Cyber-Physical Infrastructures
Industrial control systems (ICSs) have been extensively deployed in the real world. Large ICSs, such as smart power grids, consist of the supervisory control and data acquisition (SCADA) systems and the programmable logic controllers (PLCs). PLCs and SCADA exchange control signals and measurement …
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Brain Stimulation Reward is Integrated by A Network of Electrically-Coupled GABA Neurons
… GABA neurons, the degree of responding for IC ICSS is proportional to the magnitude of electrical coupling between these GABA neurons, and GJ blockers, including the Cx36 blocker mefloquine, increase the threshold for IC self-stimulation without affecting performance. Thus, electrical coupling …
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Designing Security Defenses for Cyber-Physical Systems
… transportation, and industrial control systems (ICSs), to name a few. To make matters worse, the cost of designing and deploying defenses in existing legacy infrastructure can be overwhelming as millions or even billions of legacy CPS systems are already in use. This economic angle, prevents the …
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Intrusion detection for industrial control systems
… however, due to the complexity and diversity of ICSs, well defined and reliable anomaly and intrusion detection systems are still being developed. Machine learning approaches for anomaly and intrusion detection on the network level may provide general protection that can be applied to any ICS. …
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Investigating the influence of LH-projecting BLA neurons upon motivated behavioral responding and appetitive learning
… may support intracranial self-stimulation (ICSS). Further experiments with in vivo extracellular electrophysiological recordings from LH-projecting BLA neurons may also shed light on the encoding properties of these neurons during appetitive learning.
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An Educational Framework to Support Industrial Control System Security Engineering
Industrial Control Systems (ICSs) are used to monitor and control critical infrastructure such as electricity and water. ICS were originally stand-alone systems, but are now widely being connected to corporate national IT networks, making remote monitoring and more timely control possible. While …
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Trustworthy Embedded Computing for Cyber-Physical Control
… used in large-scale industrial control systems (ICSs) manufacturing and utility infrastructure. CPC operations rely on embedded systems having real-time, high-assurance interactions with physical processes. However, recent attacks like Stuxnet have demonstrated that CPC malware is not restricted …
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The Physical Chemistry of pMDI Formulations Derived from Hydrofluoroalkane Propellants. A Study of the Physical Behaviour of Poorly Soluble Active Pharmaceutical Ingredients; Bespoke Analytical Method Development Leading to Novel Formulation Approaches for Product Development.
… between the classes of compounds with lipophilic ICSs showing the highest, and hydrophilic β2- agonist / antimuscarinics showing the lowest solubilities from the compounds under study. To determine solid forms on deposition, a series of methods are also described using modified impaction methods …
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Multi-Scale Studies to Develop a Holistic Understanding of Solid Fuel Combustion at Residential Scale
… performance and personal exposure.</p><p>Current ICSs are usually cleaner than traditional cookstoves, but still not close to the desired performance level. Therefore, cleaner fuel alternatives such as liquefied petroleum gas (LPG), natural gas, and electricity must be considered, though they …
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