Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 70 for “"ICL"”.
-
Catarata secundaria al implante de lente intraocular fáquica ICL en cámara posterior
… con implante de lente fáquica de colámero ICL modelo V4 (ICMV4) (STAAR Surgical Co.) en la cámara posterior del ojo, realizado en el Instituto Universitario Fernández-Vega, entre septiembre del 2001 y noviembre del 2010. Resultados: Fueron incluidos un total de 927 pacientes (1,705 ojos) …
-
Regulation of structure-selective nucleases by the SLX4 scaffold in ICL repair and HJ resolution
… roles in repair of DNA interstrand crosslinks (ICLs). In addition to its role in ICL repair, the SLX4 complex has the relatively unusual property of being able to cleave efficiently four-way DNA structures called Holliday junctions (HJs) in vitro. At the outset of this study a major unanswered …
-
Sphingosine-1-Phosphate and Fingolimod (FTY720) Regulate ICl,swell In HL-1 Cardiac Myocytes via Intracellular Binding And Mitochondrial ROS Production
<p>Swelling-activated Cl− current (ICl,swell) is an outwardly-rectifying current that plays an important role in cardiac electrical activity, cellular volume regulation, apoptosis, and acts as a potential effector of mechanoelectrical feedback. Persistent activation of ICl,swell has been observed …
-
ROLE OF ENDOTHELIN-1 IN THE REGULATION OF THE SWELLING-ACTIVATED Cl- CURRENT IN ATRIAL MYOCYTES
Swelling-activated Cl- current (ICl,swell) is an outwardly rectifying Cl- current that influences cardiac electric activities and acts as a potential effector of mechanoelectrical feedback that antagonizes the effects of stretch-activated cation channels. Persistent activation of ICl,swell has been …
-
FEL theory in the ION channel wiggler
The ion channel laser (ICL) is an ultra-compact version of the free-electron laser (FEL),with the wiggler replaced by an ion channel. Given its small size and the large wiggler field that can be created within a small volume, it has enormous potential for generating high-frequency coherent …
-
Separate Roles of FAN1 and Fanconi Anemia Proteins in DNA Interstrand Crosslink Repair and Human Disease
<p>DNA interstrand crosslink (ICL) repair is vital for cellular proliferation and survival. Defects in the repair of DNA crosslinks have been associated with congenital abnormalities, bone marrow and kidney failure, liver dysfunction, and cancer. DNA nucleases play a significant role during the …
-
Direct versus vicarious experiencing in a primarily nonverbal personal growth group microlab
… group experiences. The subjects responded to the ICL in two different manners. First, each subject responded to the ICL by indicating which adjectives and/or phrases were applicable to S as he saw himself (real self). Next, each subject responded to the ICL by indicating which adjectives and/or …
-
The role of the human endonuclease VIII-like 1 and 3 in the repair of DNA replication blocking lesions
… shown to resolve DNA inter-strand crosslinks (ICLs), arising from exogenous agents. Human NEIL1 (hNEIL1) activity on psoralen generated mono-adducts (MAs) and three-stranded DNA ICLs was previously described and recently NEIL3 from Xenopus laevis was reported to repair psoralen generated MAs …
-
Understanding initial capacity loss in substituted layered oxide cathodes for lithium-ion batteries
… view, demonstrating that initial capacity loss (ICL) stems from a complex interplay of bulk, surface, and interfacial kinetics rather than bulk transport alone. Electrochemical analysis of LiNiᵧCo₁₋ᵧO₂ (0 ≤ y ≤ 0.80) and ternary NMC variants (NMC111, NMC525, NMC811) identifies compositional …
-
Fancm and Faap24 Maintain Genomic Stability Through Cooperative and Unique Functions
… protecting cells from DNA interstrand crosslink (ICL) damage. Two genes involved in the FA pathway, FANCM and FAAP24, are of particular interest because they contain DNA interacting domains. However, there are no definitive patient mutations for these two genes, and the resulting lack of human …
-
Structural and mechanistic investigation towards the regulation of M.tb isocitrate lyase
Isocitrate lyase (ICL) is a crucial enzyme for the virulence and survival of Mycobacterium tuberculosis (M. tb) during infection. It is a key enzyme of the glyoxylate shunt and the methylcitrate cycle, metabolic pathways that are central to the bacteria’s carbon and lipid metabolism. The absence of …
-
The Growth of Brightest Cluster Galaxies and Intracluster Light in X-ray Selected Clusters
… galaxies and the intracluster light component (ICL) within galaxy clusters. The ICL is a flat, diffuse, low surface brightness (LSB) feature thought to contain a significant fraction of stellar mass contained within galaxy clusters; it is believed primarily to be formed from stripped stars …
-
International Crimes as Familiar Spectacles: Socially Constructed Understandings of Atrocity and the Visibility Politics of International Criminal Law
… and the substance of international criminal law (ICL). Chapter one, combining insights from interactional legal theory and the field of neuroaesthetics, theorizes ICL as an environment conducive to aesthetic considerations influencing relevant norm development processes. Chapter two, through an …
-
Inference-Time Learning Algorithms of Language Models
… complex tasks through in-context learning (ICL)—they can adapt to a task via examples provided in their input without any parameter updates. However, fundamental questions remain about when this adaptation works, what algorithms underlie it, and how to improve it. This thesis studies the …
-
Light-emitting diodes as an alternative supplemental lighting source for greenhouse tomato propagation and production
… energy consumption using intracanopy lighting (ICL) with LEDs (ICL-LED) or OH-HPS lamps as different SL sources and positions for high-wire greenhouse tomato production; 3) compare crop physiological responses to different SL sources and positions [ICL-LED vs. OH-HPS vs. hybrid lighting (ICL-LED …
-
Novel Inhibitors for Isocitrate Lyase as a Potent Antitubercular Agent for Mycobacterium Tuberculosis
… has been shown that the enzyme isocitrate lyase (ICL) is essential for the survival and persistence of Mtb in latent TB. ICL plays an important role in two metabolic pathways required during TB latency, the glyoxylate and methylcitrate cycle. ICL is absent in humans, and therefore, it is …
-
Modeling Integrated Cortical Learning: Explorations of Cortical Map Development, Unit Selectivity, and Object Recognition
… called the Integrated Cortical Learning Model (ICL). As part of these efforts I also introduce novel methods for incorporating axonal learning and development into artificial neural networks called the Axon Game and the Arbor Layer. I examined the utility of this new cortical model in three main …
-
Nucleotide Excision Repair, Crosslink Repair and Transcriptional Function of Xpa In Human Cells
… mammalian cells to DNA interstrand crosslinks (ICL)-generating agents. I found that XPA is retained on damaged DNA following exposure to UVA-activated psoralen, and investigated repair of a triplex forming oligonucleotide (TFO)-directed psoralen ICL. A TFO-directed psoralen DNA ICL was …
-
Relationship of Mechanical Deformations and Electrochemical Properties of Lithium Ion Batteries-An Experimental Study
MIT’s Impact & Crashworthiness Lab (ICL) has been conducting research into lithium-ion batteries in an effort to produce a computation model that can predict the impact of mechanical deformations on electrochemical properties of lithium-ion batteries. Experiments were conducted on two different …
-
Fanconi Anaemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mammalian development
… Fanconi Anaemia DNA inter-strand crosslink (FA ICL) repair factors act in concert to restrict LINE-1 retrotransposition. Moreover, by purifying the recombinant FA ICL repair incision complex (SLX4-XPF-ERCC1), I show that it can cleave intermediates of retrotransposition, aborting new …
Page 1 of 4